Top 5 Acne Serums in Canada, 2025

The Ordinary Niacinamide 10% + Zinc 1% is a standout serum known for its high concentration of niacinamide, which helps to regulate sebum production and reduce the appearance of blemishes. With the added benefit of zinc, this product not only aids in acne management but also provides anti-inflammatory properties. The lightweight formula absorbs quickly, making it suitable for all skin types. Its affordability combined with effective results makes it a favorite among skincare enthusiasts.

Paula’s Choice 10% Niacinamide Booster is a powerful serum specifically designed to improve skin texture and minimize enlarged pores. This booster stands out by delivering a potent dose of niacinamide combined with antioxidants to enhance skin barrier function and impart a youthful glow. Its easily adjustable formula allows users to mix it with other products, maximizing its adaptability to personal skincare routines. Renowned for its transparency in ingredients and efficacy, Paula’s Choice remains a trusted name in skincare.

Drunk Elephant T.L.C. Framboos Glycolic Night Serum is a multi-faceted product that combines glycolic, lactic, tartaric, citric, and salicylic acids for gentle exfoliation while you sleep. What sets it apart is its blend of both AHA and BHA, allowing for improved skin texture, reduced fine lines, and clearer pores without irritating the skin. Free from harmful ingredients, this serum promotes a balanced complexion and helps all skin types glow. The commitment to clean formulations positions Drunk Elephant as a leader in the skincare industry.

Murad Rapid Relief Acne Spot Treatment is a fast-acting solution that provides targeted care for pesky pimples. Its unique formulation boasts a blend of salicylic acid and other acne-fighting ingredients that work quickly to reduce redness and inflammation without drying out the surrounding skin. Users appreciate the visible results within hours, making it a go-to for those needing quick relief. Murad's reputation for high-quality ingredients and effective skincare solidifies its position as a market leader.