Top 5 Eye Allergy Drops in Canada for 2026

Alaway Antihistamine Eye Drops are built around ketotifen fumarate 0.035% (equivalent to ketotifen 0.025%), a dual-action antihistamine and mast-cell stabilizer that targets both the cause and the symptoms of eye allergies, with up to 12-hour relief from a twice-daily dose. The standard multi-dose bottle is preserved with benzalkonium chloride, so contact lens wearers should remove lenses before use and wait about 10 minutes before reinserting. Important for Canadian buyers: Alaway carries a US NDC and has no Health Canada DIN, so it is not authorized for sale in Canada. It is an over-the-counter staple in the United States, and the ketotifen product authorized in Canada is Zaditor, which requires a prescription.

Pataday Once Daily Relief Extra Strength is an olopatadine hydrochloride 0.7% eye drop that blocks histamine and stabilizes mast cells, giving up to 24 hours of relief from allergic itching with a single drop per eye per day. Two things matter for Canadian buyers. First, olopatadine ophthalmic solution is a prescription drug in Canada, so it is not sold over the counter here the way it is in the United States. Second, the 0.7% Extra Strength concentration itself is not authorized in Canada: the Pataday that Health Canada has approved is olopatadine 0.2% (DIN 02362171), dosed once daily and also prescription-only. It is a reasonable step up to discuss with a prescriber when an over-the-counter drop is not controlling symptoms.

Zaditor Antihistamine Eye Drops deliver up to 12 hours of relief from allergic itching. The active ingredient is ketotifen 0.025% (equivalent to ketotifen fumarate 0.035%), the same dual-action antihistamine and mast-cell stabilizer found in Alaway, dosed one drop in each eye twice daily and suitable for adults and children ages 3 and up. The standard multi-dose bottle is preserved with benzalkonium chloride, so remove soft contact lenses first and wait at least 10 minutes before reinserting. Note the Canadian status: Zaditor is authorized by Health Canada under DIN 02242324 as a prescription drug, so unlike in the United States it is not an off-the-shelf purchase here.

Bepreve (bepotastine besilate 1.5% w/v) is a prescription eye drop for the itching associated with allergic conjunctivitis. It is a dual-action agent: it blocks the H1 histamine receptor and stabilizes mast cells, dosed one drop in each affected eye twice daily. Health Canada has authorized it under DIN 02456532, marketed by Bausch & Lomb, and it is prescription-only, so it is obtained through a physician, optometrist, or other authorized prescriber rather than bought off the shelf. It is the most potent option listed here and is generally considered when milder drops have not controlled symptoms.

OPTASE Allegro is a preservative-free lubricating eye drop built for allergy-related dry eye and environmental-irritant relief rather than a histamine-blocking antihistamine. It pairs hydroxyethylcellulose, which coats and stabilizes the tear film, with ectoin, a naturally derived molecule that forms a protective hydro-shield over the ocular surface to guard against pollen, dust, and other airborne triggers. Because it is preservative-free and dispensed from a 10 mL multidose bottle rated for about 300 drops, it is gentle enough for frequent use and compatible with contact lenses. Choose Allegro to wash away and buffer allergens and soothe gritty, irritated eyes. It is a lubricant rather than a scheduled drug, so unlike the antihistamine drops on this page it can simply be bought; pair it with an over-the-counter cromolyn drop, or with a prescribed antihistamine drop, when the main complaint is intense itching.