Douxo S3 PYO Shampoo
Douxo S3 PYO is regarded as best-in-class for medicated cat shampoo because it combines antiseptic/antifungal actives with phytosphingosine-based barrier support, making it especially effective for pyoderma and complex dermatologic cases. Compared with the other products in this list it offers advanced skin‑barrier repair and a clinician-preferred formulation, though it is typically priced higher than basic antiseptic shampoos which reflects its technical advantages for long-term skin health.
Phytosphingosine shield
Gentle skin hug
Phytosphingosine shield
Gentle skin hug
Review Summary
"Cat owners report fast, reliable improvement in bacterial/yeast skin infections with Douxo S3 PYO; it’s pleasantly scented and not overly drying, though it’s more expensive than generic options."
Soothes itchy drama
Veterinary-strength antibacterial and antifungal formula effective for yeast and pyoderma.
Soothes itchy drama
Veterinary-strength antibacterial and antifungal formula effective for yeast and pyoderma.
Increased Safety & Security
Time-Saving Convenience
Douxo S3 PYO is regarded as best-in-class for medicated cat shampoo because it combines antiseptic/antifungal actives with phytosphingosine-based barrier support, making it especially effective for pyoderma and complex dermatologic cases. Compared with the other products in this list it offers advanced skin‑barrier repair and a clinician-preferred formulation, though it is typically priced higher than basic antiseptic shampoos which reflects its technical advantages for long-term skin health.
Phytosphingosine shield
Gentle skin hug
Soothes itchy drama
Veterinary-strength antibacterial and antifungal formula effective for yeast and pyoderma.
Includes moisturizing agents to help protect and repair the skin barrier.
Phytosphingosine shield
Gentle skin hug
Soothes itchy drama
Veterinary-strength antibacterial and antifungal formula effective for yeast and pyoderma.
Includes moisturizing agents to help protect and repair the skin barrier.
$30-45 CAD
Malaseb Medicated Shampoo
Malaseb is a market-leading, widely used medicated shampoo known for reliable antibacterial and antifungal activity, making it a go-to first-line treatment for yeast and bacterial skin infections in cats. Compared with Douxo it does not emphasize lipid-based barrier restoration but is often more budget-friendly and broadly stocked by clinics, delivering strong clinical efficacy at a lower cost for routine therapeutic use.
Dual-action clean
Fights yeast fiesta
Dual-action clean
Fights yeast fiesta
Review Summary
"Users say Malaseb consistently clears yeast and bacterial issues in cats and is a common veterinary recommendation, but some note a medicinal smell and potential to dry the coat if overused."
Dermal relief fast
Contains established antifungal and antibacterial actives commonly used to treat ringworm, yeast, and bacterial infections.
Dermal relief fast
Contains established antifungal and antibacterial actives commonly used to treat ringworm, yeast, and bacterial infections.
Increased Safety & Security
Time-Saving Convenience
Malaseb is a market-leading, widely used medicated shampoo known for reliable antibacterial and antifungal activity, making it a go-to first-line treatment for yeast and bacterial skin infections in cats. Compared with Douxo it does not emphasize lipid-based barrier restoration but is often more budget-friendly and broadly stocked by clinics, delivering strong clinical efficacy at a lower cost for routine therapeutic use.
Dual-action clean
Fights yeast fiesta
Dermal relief fast
Contains established antifungal and antibacterial actives commonly used to treat ringworm, yeast, and bacterial infections.
Effective for medicated bathing protocols prescribed by veterinarians.
Dual-action clean
Fights yeast fiesta
Dermal relief fast
Contains established antifungal and antibacterial actives commonly used to treat ringworm, yeast, and bacterial infections.
Effective for medicated bathing protocols prescribed by veterinarians.
$25-40 CAD
Veterinary Formula Clinical Care Antiseptic & Antifungal Shampoo
Veterinary Formula Clinical Care Antiseptic & Antifungal Shampoo offers an accessible over-the-counter balance of antiseptic and antifungal activity tailored for at-home management and maintenance care. Technically it tends to be less concentrated than prescription products like Malaseb or Douxo, which makes it gentler for frequent use and often lowers per-treatment cost while preserving retail availability for owners.
Antiseptic powerwash
pH-balanced cuddle
Antiseptic powerwash
pH-balanced cuddle
Review Summary
"Many cat owners find Veterinary Formula Clinical Care Antiseptic & Antifungal Shampoo a good budget option that reduces itching and odor, though multiple washes are often needed and it can be less potent than prescription products."
Veterinary trusted flair
Combines antiseptic and antifungal ingredients for broad-spectrum skin cleansing.
Veterinary trusted flair
Combines antiseptic and antifungal ingredients for broad-spectrum skin cleansing.
Increased Safety & Security
Time-Saving Convenience
Veterinary Formula Clinical Care Antiseptic & Antifungal Shampoo offers an accessible over-the-counter balance of antiseptic and antifungal activity tailored for at-home management and maintenance care. Technically it tends to be less concentrated than prescription products like Malaseb or Douxo, which makes it gentler for frequent use and often lowers per-treatment cost while preserving retail availability for owners.
Antiseptic powerwash
pH-balanced cuddle
Veterinary trusted flair
Combines antiseptic and antifungal ingredients for broad-spectrum skin cleansing.
Affordable choice for routine medicated baths and ongoing symptom control.
Antiseptic powerwash
pH-balanced cuddle
Veterinary trusted flair
Combines antiseptic and antifungal ingredients for broad-spectrum skin cleansing.
Affordable choice for routine medicated baths and ongoing symptom control.
$15-30 CAD
Curaseb Antifungal & Antibacterial Chlorhexidine Shampoo
Curaseb Antifungal & Antibacterial Chlorhexidine Shampoo emphasizes potent chlorhexidine antisepsis for rapid reduction of bacterial and fungal load, making it a practical choice for acute infections that require strong antimicrobial action. Financially it often undercuts premium veterinary lines while delivering robust antibacterial performance, though it lacks the dedicated barrier-repair or enzymatic approaches found in Douxo and Zymox respectively.
Chlorhexidine punch
Persistent odor zap
Chlorhexidine punch
Persistent odor zap
Review Summary
"Users report Curaseb effectively controls fungal and bacterial issues in cats with a gentle feel and generally pleasant scent; a minority experience mild drying but overall results are strong."
Clinic-strength spa
Chlorhexidine-based formulation targets bacteria while offering antifungal activity.
Clinic-strength spa
Chlorhexidine-based formulation targets bacteria while offering antifungal activity.
Increased Safety & Security
Time-Saving Convenience
Curaseb Antifungal & Antibacterial Chlorhexidine Shampoo emphasizes potent chlorhexidine antisepsis for rapid reduction of bacterial and fungal load, making it a practical choice for acute infections that require strong antimicrobial action. Financially it often undercuts premium veterinary lines while delivering robust antibacterial performance, though it lacks the dedicated barrier-repair or enzymatic approaches found in Douxo and Zymox respectively.
Chlorhexidine punch
Persistent odor zap
Clinic-strength spa
Chlorhexidine-based formulation targets bacteria while offering antifungal activity.
Helps reduce microbial load and soothe inflamed skin during treatment courses.
Chlorhexidine punch
Persistent odor zap
Clinic-strength spa
Chlorhexidine-based formulation targets bacteria while offering antifungal activity.
Helps reduce microbial load and soothe inflamed skin during treatment courses.
$25-40 CAD
Zymox Enzymatic Shampoo
Zymox Enzymatic Shampoo uses a proprietary enzyme system to deliver natural antimicrobial activity, providing a gentler, steroid-sparing approach that can be better tolerated on sensitive feline skin. Compared with the chemical antiseptic-based shampoos on this list it offers a unique non-antibiotic mechanism and may reduce irritation, though it is often priced higher per bottle and can act more gradually in severe infections.
Enzyme clean magic
Non-antibiotic calm
Enzyme clean magic
Non-antibiotic calm
Review Summary
"Owners praise Zymox Enzymatic Shampoo for its gentle, enzyme-based approach that soothes chronic skin problems without harsh chemicals, though it’s pricier and can be slower on severe infections."
Bio-active bubble
Uses enzymatic technology to support natural skin defenses and reduce microbial burden.
Bio-active bubble
Uses enzymatic technology to support natural skin defenses and reduce microbial burden.
Increased Safety & Security
Time-Saving Convenience
Zymox Enzymatic Shampoo uses a proprietary enzyme system to deliver natural antimicrobial activity, providing a gentler, steroid-sparing approach that can be better tolerated on sensitive feline skin. Compared with the chemical antiseptic-based shampoos on this list it offers a unique non-antibiotic mechanism and may reduce irritation, though it is often priced higher per bottle and can act more gradually in severe infections.
Enzyme clean magic
Non-antibiotic calm
Bio-active bubble
Uses enzymatic technology to support natural skin defenses and reduce microbial burden.
Non-antibiotic option that may reduce irritation and support healing when used appropriately.
Enzyme clean magic
Non-antibiotic calm
Bio-active bubble
Uses enzymatic technology to support natural skin defenses and reduce microbial burden.
Non-antibiotic option that may reduce irritation and support healing when used appropriately.