Revolution Plus for Cats earns a top spot for its broad-spectrum protection — it addresses fleas, ticks, ear mites and several intestinal parasites while also preventing heartworm, reducing the need for multiple separate products. That technical breadth makes it more versatile than flea-only options like Advantage II or Frontline Plus, and although its per-dose price is typically higher, the consolidated coverage can be more cost-efficient for multi-threat households compared with buying several single-purpose treatments.
Broad parasite coverage
Simple monthly dose
Broad parasite coverage
Simple monthly dose
Review Summary
"Most long-term users praise Revolution Plus for reliably preventing fleas and ticks with sustained protection, though a minority report occasional mild skin or digestive reactions and note a higher price point."
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus for Cats earns a top spot for its broad-spectrum protection — it addresses fleas, ticks, ear mites and several intestinal parasites while also preventing heartworm, reducing the need for multiple separate products. That technical breadth makes it more versatile than flea-only options like Advantage II or Frontline Plus, and although its per-dose price is typically higher, the consolidated coverage can be more cost-efficient for multi-threat households compared with buying several single-purpose treatments.
Broad parasite coverage
Simple monthly dose
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Provides protection against fleas, several tick species and other external parasites and contributes to heartworm prevention.
Broad parasite coverage
Simple monthly dose
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Provides protection against fleas, several tick species and other external parasites and contributes to heartworm prevention.
$170-240 CAD
Revolution Plus for Cats
Revolution Plus combines selamectin and sarolaner in a topical, broad‑spectrum formulation that treats roundworms and hookworms while also delivering strong flea and tick control, making it a top pick for cat owners who want one product to cover both intestinal and external parasites. Compared with single‑purpose anthelmintics on this list, its combination chemistry reduces the need to buy separate flea and deworming treatments, often improving value for multi‑parasite prevention. Its technical advantage is the proven dual activity profile, while financially it can be cost‑effective by consolidating two treatment needs into one monthly application.
Broad parasite shield
Monthly easy-apply
Broad parasite shield
Monthly easy-apply
Review Summary
"Most users report fast, reliable control of fleas, ticks, and intestinal worms with convenient monthly topical dosing; a minority report mild side effects like transient skin irritation or upset stomach."
Tick-flea knockout
Monthly topical combining selamectin and sarolaner to control fleas, ticks, ear mites and many intestinal parasites (roundworms, hookworms).
Tick-flea knockout
Monthly topical combining selamectin and sarolaner to control fleas, ticks, ear mites and many intestinal parasites (roundworms, hookworms).
Increased Safety & Security
Time-Saving Convenience
Revolution Plus combines selamectin and sarolaner in a topical, broad‑spectrum formulation that treats roundworms and hookworms while also delivering strong flea and tick control, making it a top pick for cat owners who want one product to cover both intestinal and external parasites. Compared with single‑purpose anthelmintics on this list, its combination chemistry reduces the need to buy separate flea and deworming treatments, often improving value for multi‑parasite prevention. Its technical advantage is the proven dual activity profile, while financially it can be cost‑effective by consolidating two treatment needs into one monthly application.
Broad parasite shield
Monthly easy-apply
Tick-flea knockout
Monthly topical combining selamectin and sarolaner to control fleas, ticks, ear mites and many intestinal parasites (roundworms, hookworms).
Also formulated to prevent heartworm disease when used monthly as directed.
Broad parasite shield
Monthly easy-apply
Tick-flea knockout
Monthly topical combining selamectin and sarolaner to control fleas, ticks, ear mites and many intestinal parasites (roundworms, hookworms).
Also formulated to prevent heartworm disease when used monthly as directed.
$70-110 CAD
Revolution Plus for Cats
Revolution Plus holds a best-in-class position as a premium monthly spot-on that combines strong flea and tick control with intestinal parasite coverage, making it a go-to for cat owners seeking comprehensive protection in a single application. Compared with the other products in this list it is positioned as a high-efficacy, widely studied option with a strong safety profile, trading a higher per-dose price for broad multi-parasite coverage and predictable monthly dosing. For the specific use case of spot-on combination flea, tick and intestinal worm treatments, its technical reliability and market availability justify its leader status.
Parasite party pooper
Monthly stress-buster
Parasite party pooper
Monthly stress-buster
Review Summary
"Users report Revolution Plus is highly effective at preventing fleas, ticks, ear mites and several intestinal worms with fast, reliable results and few adverse reactions; many owners praise its single monthly topical application. Some note occasional mild skin reactions or temporary lethargy in sensitive cats."
Tiny tick karate
Topical monthly treatment combining selamectin + sarolaner to protect against fleas and ticks.
Tiny tick karate
Topical monthly treatment combining selamectin + sarolaner to protect against fleas and ticks.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus holds a best-in-class position as a premium monthly spot-on that combines strong flea and tick control with intestinal parasite coverage, making it a go-to for cat owners seeking comprehensive protection in a single application. Compared with the other products in this list it is positioned as a high-efficacy, widely studied option with a strong safety profile, trading a higher per-dose price for broad multi-parasite coverage and predictable monthly dosing. For the specific use case of spot-on combination flea, tick and intestinal worm treatments, its technical reliability and market availability justify its leader status.
Parasite party pooper
Monthly stress-buster
Tiny tick karate
Topical monthly treatment combining selamectin + sarolaner to protect against fleas and ticks.
Also prevents heartworm and treats intestinal roundworms and hookworms plus ear mites.
Parasite party pooper
Monthly stress-buster
Tiny tick karate
Topical monthly treatment combining selamectin + sarolaner to protect against fleas and ticks.
Also prevents heartworm and treats intestinal roundworms and hookworms plus ear mites.
$300-450 CAD
Revolution Plus combines a broad-spectrum topical formulation that targets fleas, ticks, mites and lice with a reputation for strong clinical efficacy, making it a top choice for veterinary-recommended mite and lice control. It typically commands a premium price but offers a technically comprehensive single-product approach that reduces the need for multiple treatments compared with lower-cost OTC options in this list.
Broad parasite coverage
Monthly topical dose
Broad parasite coverage
Monthly topical dose
Review Summary
"Users report reliable, broad-spectrum protection against fleas, ticks, and common parasites with few side effects; most praise the monthly convenience and consistent effectiveness."
Vet-approved superpower
Prescription topical combining selamectin and sarolaner for wide parasite coverage.
Vet-approved superpower
Prescription topical combining selamectin and sarolaner for wide parasite coverage.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus combines a broad-spectrum topical formulation that targets fleas, ticks, mites and lice with a reputation for strong clinical efficacy, making it a top choice for veterinary-recommended mite and lice control. It typically commands a premium price but offers a technically comprehensive single-product approach that reduces the need for multiple treatments compared with lower-cost OTC options in this list.
Broad parasite coverage
Monthly topical dose
Vet-approved superpower
Prescription topical combining selamectin and sarolaner for wide parasite coverage.
Monthly dosing prevents heartworm and controls fleas, many tick species and ear mites.
Broad parasite coverage
Monthly topical dose
Vet-approved superpower
Prescription topical combining selamectin and sarolaner for wide parasite coverage.
Monthly dosing prevents heartworm and controls fleas, many tick species and ear mites.
$90-150 CAD
Bravecto Plus for Cats is positioned as the long‑duration tick specialist in this list, offering extended protection that reduces dosing frequency compared with monthly spot‑ons and can lower annual treatment costs for owners who value convenience. Technically it stands out for its sustained activity against ticks between doses, making it a strong choice for cat owners in high‑tick areas when compared to shorter‑acting competitors like Revolution Plus or Frontline Plus.
12-week protection
Covers fleas & ticks
12-week protection
Covers fleas & ticks
Review Summary
"Users report Bravecto Plus delivers long-lasting, highly effective tick and flea control with the convenience of multi-month protection; most owners praise efficacy and low dosing frequency while a small minority note mild, transient side effects. Overall feedback emphasizes excellent parasite control and fewer monthly treatments."
Single-dose ease (nap-friendly)
Provides up to 12 weeks protection against ticks and fleas per application.
Single-dose ease (nap-friendly)
Provides up to 12 weeks protection against ticks and fleas per application.
Increased Safety & Security
Time-Saving Convenience
Bravecto Plus for Cats is positioned as the long‑duration tick specialist in this list, offering extended protection that reduces dosing frequency compared with monthly spot‑ons and can lower annual treatment costs for owners who value convenience. Technically it stands out for its sustained activity against ticks between doses, making it a strong choice for cat owners in high‑tick areas when compared to shorter‑acting competitors like Revolution Plus or Frontline Plus.
12-week protection
Covers fleas & ticks
Single-dose ease (nap-friendly)
Provides up to 12 weeks protection against ticks and fleas per application.
Contains fluralaner combined with moxidectin for broad parasite coverage including some intestinal worms.
12-week protection
Covers fleas & ticks
Single-dose ease (nap-friendly)
Provides up to 12 weeks protection against ticks and fleas per application.
Contains fluralaner combined with moxidectin for broad parasite coverage including some intestinal worms.
$180-280 CAD