Top 6 Antifungal and Antibacterial Topical Treatments in Canada (2025) — Vet-Trusted, Cat-Safe Creams, Ointments & Sprays with Guided Treatment Plans

Douxo S3 PYO Mousse (Ceva) is a veterinary‑grade foam formulated to target bacterial and fungal flare‑ups with actives optimized for pyoderma and Malassezia, and the mousse texture improves application and adherence on the coat and skin. As a premium, clinician‑focused product it typically carries a higher price than sprays or gels, but delivers superior targeted efficacy and handling compared with broad antiseptics, making it the market leader for prescribers seeking both potency and user‑friendly performance.

Bayer Miconahex + Triz Spray leverages Bayer’s pharmaceutical manufacturing standards to deliver a robust, clinically validated antiseptic combination that targets both fungi and bacteria, making it a go-to for more severe or persistent infections. Its technical strength and regulatory backing make it a higher-cost, higher-efficacy option compared with gentler or enzymatic products (for example, Zymox), and it’s often preferred where strong, predictable antimicrobial activity is required.

Douxo S3 PYO Mousse is a veterinarian-grade mousse designed to restore skin barrier function while addressing bacterial and fungal overgrowth, making it a market-leading choice for clinically driven dermatologic care in cats. Although it is a mousse rather than a powder, its targeted barrier-restorative ingredients and clinical backing often outperform powders such as Veterinary Formula or Gold Bond for moderate-to-severe or widespread skin conditions, albeit at a higher cost. For cats that do not tolerate powders or require evidence-backed dermatologic therapy, Douxo represents a premium, clinically focused option.

Douxo S3 PYO Mousse is a premium mousse applicator that pairs antiseptic agents with skin-barrier supporting phytosphingosine, designed to treat pyoderma-prone areas while restoring coat and epidermal health; its mousse format makes application to cats quick and owner-friendly. As a market leader for barrier repair and maintenance, Douxo often commands a higher price but can reduce recurrence when compared to single-action antiseptics, offering a technically advanced, convenience-focused option in this product set.

Vetericyn Plus is positioned as a gentle, non‑antibiotic antimicrobial spray tailored for cats, favored for its broad-spectrum, no‑rinse formulation that supports wound cleansing without harsh ingredients — a technical advantage for frequent use on sensitive feline skin. Compared with enzyme‑based or steroid‑containing options on this list, Vetericyn’s non‑steroidal oxidizing approach reduces reliance on antibiotics and often represents a cost‑effective first step for superficial wounds and lesions before moving to prescription antifungal or antibacterial therapies.