I N C E P T I O N A I
  1. Pet supplies
  2. Cats
  3. Cat health supplies
  4. Cat vitamins supplements
  5. Immune antioxidant support

Top 5 Immune & Antioxidant Support for Cats in Canada (2025) — Veterinarian-Reviewed Picks to Protect Your Cat

Published on Wednesday, August 20, 2025

Formulas with antioxidants, vitamins, and immune modulators are designed to help defend cats against oxidative stress and support natural immune function. This category includes products that combine vitamin C analogs, vitamin E, beta-glucans, L-lysine and other trending immune-support ingredients in cat-friendly formats such as chews, powders and liquid drops. In Canada, pet owners increasingly choose supplements that are veterinarian-reviewed, third-party tested, and manufactured to good-practice standards; they also value transparent ingredient sourcing, easy dosing options for picky cats, and products available through trusted Canadian retailers or with cross-border shipping options. These consumer preferences shape which formulas gain traction: those that balance clinically relevant ingredients, clear dosage guidance, and reliable quality assurance tend to be the most appealing in the market.

Quick Menu

1. Best Budget Immune Lysine

2. Best Daily Antioxidant Blend

3. Best Veterinary-Grade Lysine

4. Best Value Pure L-Lysine

5. Best Premium Antioxidant & Probiotic

1
BEST BUDGET IMMUNE LYSINE

NaturVet Lysine Plus Immune Support for Cats

Pet Honesty

NaturVet Lysine Plus is positioned as a cost-effective, widely available lysine-based immune support tailored for cat owners seeking basic antiviral and antioxidant help. It stands out for its retail presence and budget-friendly dosing compared with premium veterinary lines like VetriScience and Pet Wellbeing, though it is less concentrated and formulaically simpler than those higher-end options. For shoppers prioritizing value and familiarity in everyday immune maintenance, NaturVet delivers a straightforward lysine-centric approach.

4.4
★★★★☆
  • Lysine boost

  • Antioxidant blend

  • Lysine boost

  • Antioxidant blend

Review Summary

86%

"Most cat owners find it palatable and helpful for reducing URI flare-ups and improving nasal/eye discharge over time, though a minority report no noticeable benefit."

  • Purr-worthy chew

  • L-lysine formulation to support upper respiratory immune response in cats.

  • Purr-worthy chew

  • L-lysine formulation to support upper respiratory immune response in cats.

Increased Safety & Security

Recreational Enjoyment

NaturVet Lysine Plus is positioned as a cost-effective, widely available lysine-based immune support tailored for cat owners seeking basic antiviral and antioxidant help. It stands out for its retail presence and budget-friendly dosing compared with premium veterinary lines like VetriScience and Pet Wellbeing, though it is less concentrated and formulaically simpler than those higher-end options. For shoppers prioritizing value and familiarity in everyday immune maintenance, NaturVet delivers a straightforward lysine-centric approach.

  • Lysine boost

  • Antioxidant blend

  • Purr-worthy chew

  • L-lysine formulation to support upper respiratory immune response in cats.

  • Palatable chewable tablets designed for easy daily dosing.

  • Lysine boost

  • Antioxidant blend

  • Purr-worthy chew

  • L-lysine formulation to support upper respiratory immune response in cats.

  • Palatable chewable tablets designed for easy daily dosing.

Order Now
-10%22.49$
Suggested Price: 24.99$
2
BEST DAILY ANTIOXIDANT BLEND

Zesty Paws Core Elements Daily Immune Support for Cats

Zesty Paws

Zesty Paws Core Elements Daily Immune Support combines a multi-ingredient antioxidant and immune blend with palatable delivery, making it a strong mid-priced choice for daily support. Compared with single-ingredient lysine products (NOW, NaturVet) it offers broader botanical and nutrient coverage, while costing less than some premium veterinary formulations—so it balances ingredient breadth and affordability for owners who want more than basic lysine. Its technical advantage is the multi-target formulation aimed at both antioxidant defense and general immune resilience.

4.5
★★★★☆
  • Daily defense

  • Antioxidant core

  • Daily defense

  • Antioxidant core

Review Summary

88%

"Users praise the taste and convenience and report fewer respiratory symptoms and improved energy with regular use; a few note slow results or no change."

  • Tail-twitch treat

  • Multi-ingredient formula combining immune modulators and antioxidants for daily use.

  • Tail-twitch treat

  • Multi-ingredient formula combining immune modulators and antioxidants for daily use.

Increased Safety & Security

Recreational Enjoyment

Zesty Paws Core Elements Daily Immune Support combines a multi-ingredient antioxidant and immune blend with palatable delivery, making it a strong mid-priced choice for daily support. Compared with single-ingredient lysine products (NOW, NaturVet) it offers broader botanical and nutrient coverage, while costing less than some premium veterinary formulations—so it balances ingredient breadth and affordability for owners who want more than basic lysine. Its technical advantage is the multi-target formulation aimed at both antioxidant defense and general immune resilience.

  • Daily defense

  • Antioxidant core

  • Tail-twitch treat

  • Multi-ingredient formula combining immune modulators and antioxidants for daily use.

  • Includes ingredients like colostrum and beta-glucans to bolster immune resilience.

  • Daily defense

  • Antioxidant core

  • Tail-twitch treat

  • Multi-ingredient formula combining immune modulators and antioxidants for daily use.

  • Includes ingredients like colostrum and beta-glucans to bolster immune resilience.

Order Now
From 24.97$
3
BEST VETERINARY-GRADE LYSINE

VetriScience Vetri Lysine Plus

VetriScience

VetriScience Vetri Lysine Plus is presented as a veterinary-focused, higher-potency lysine formula that appeals to owners seeking a clinically-minded, brand-trusted supplement. It differentiates itself from mainstream retail brands through a reputation for veterinary quality control and slightly higher active concentrations, justifying its premium price compared with budget lysine options like NOW and NaturVet. For cat caregivers wanting a vet-oriented lysine product with reliable manufacturing pedigree, VetriScience is a market leader choice.

4.6
★★★★☆
  • Veterinary strength

  • Cold-fighting lysine

  • Veterinary strength

  • Cold-fighting lysine

Review Summary

90%

"Veterinarians and owners commonly report it helps control feline herpes/URI symptoms, is well tolerated and palatable, though severe cases may see limited improvement."

  • Pocket-pill perk

  • Veterinarian-formulated L-lysine product targeted at reducing viral replication in the upper respiratory tract.

  • Pocket-pill perk

  • Veterinarian-formulated L-lysine product targeted at reducing viral replication in the upper respiratory tract.

Increased Safety & Security

Time-Saving Convenience

VetriScience Vetri Lysine Plus is presented as a veterinary-focused, higher-potency lysine formula that appeals to owners seeking a clinically-minded, brand-trusted supplement. It differentiates itself from mainstream retail brands through a reputation for veterinary quality control and slightly higher active concentrations, justifying its premium price compared with budget lysine options like NOW and NaturVet. For cat caregivers wanting a vet-oriented lysine product with reliable manufacturing pedigree, VetriScience is a market leader choice.

  • Veterinary strength

  • Cold-fighting lysine

  • Pocket-pill perk

  • Veterinarian-formulated L-lysine product targeted at reducing viral replication in the upper respiratory tract.

  • Made to pharmaceutical-quality standards for reliable dosing and potency.

  • Veterinary strength

  • Cold-fighting lysine

  • Pocket-pill perk

  • Veterinarian-formulated L-lysine product targeted at reducing viral replication in the upper respiratory tract.

  • Made to pharmaceutical-quality standards for reliable dosing and potency.

Order Now

$30-45 CAD

4
BEST VALUE PURE L-LYSINE

NOW Pets L-Lysine for Cats

NOW

NOW Pets L-Lysine for Cats is a no-frills, purity-focused lysine supplement that offers excellent cost-per-gram and transparent ingredient sourcing for owners focused on a single-nutrient intervention. Unlike multi-nutrient antioxidant blends (Zesty Paws, Pet Wellbeing), NOW emphasizes raw L-lysine purity and affordability, making it the technically simplest and often least expensive option for targeted lysine supplementation. It’s a practical pick for those who want to add lysine without paying for extra botanicals or proprietary blends.

4.3
★★★★☆
  • Concentrated L-lysine

  • Clean formula

  • Concentrated L-lysine

  • Clean formula

Review Summary

82%

"An affordable, pure L-lysine option that many owners use effectively for URI prevention; some cats resist the powder and a minority of users notice no benefit."

  • Human-grade hero

  • Pure L-lysine supplement that supports immune function and upper respiratory health.

  • Human-grade hero

  • Pure L-lysine supplement that supports immune function and upper respiratory health.

Increased Safety & Security

Time-Saving Convenience

NOW Pets L-Lysine for Cats is a no-frills, purity-focused lysine supplement that offers excellent cost-per-gram and transparent ingredient sourcing for owners focused on a single-nutrient intervention. Unlike multi-nutrient antioxidant blends (Zesty Paws, Pet Wellbeing), NOW emphasizes raw L-lysine purity and affordability, making it the technically simplest and often least expensive option for targeted lysine supplementation. It’s a practical pick for those who want to add lysine without paying for extra botanicals or proprietary blends.

  • Concentrated L-lysine

  • Clean formula

  • Human-grade hero

  • Pure L-lysine supplement that supports immune function and upper respiratory health.

  • Simple, single-ingredient formulation suitable for long-term use or stacking with other supplements.

  • Concentrated L-lysine

  • Clean formula

  • Human-grade hero

  • Pure L-lysine supplement that supports immune function and upper respiratory health.

  • Simple, single-ingredient formulation suitable for long-term use or stacking with other supplements.

Order Now
From 24.95$
5
BEST PREMIUM ANTIOXIDANT & PROBIOTIC

Pet Wellbeing Life Gold for Cats

Pet Wellbeing

Pet Wellbeing Life Gold for Cats is a premium, broad-spectrum immune and antioxidant formula designed for comprehensive long-term support, combining vitamins, antioxidants and fatty acids in a palatable format. It stands apart from single-ingredient lysine supplements by offering a more holistic nutrient profile and typically higher per-unit cost, positioned for owners who prefer an all-in-one, higher-end regimen rather than piecemeal additions. Technically and financially, Life Gold targets customers willing to invest in a consolidated, high-quality maintenance formula rather than basic lysine alone.

4.7
★★★★☆
  • Broad-spectrum support

  • Antioxidant-rich formula

  • Broad-spectrum support

  • Antioxidant-rich formula

Review Summary

92%

"Owners frequently report improved coat condition, energy and immune resilience with consistent use; it's regarded as high-quality but is pricier and not an instant fix for every cat."

  • Drop-and-go mix

  • Comprehensive multi-nutrient formula combining antioxidants, essential fatty acids, and probiotics to support immunity and digestion.

  • Drop-and-go mix

  • Comprehensive multi-nutrient formula combining antioxidants, essential fatty acids, and probiotics to support immunity and digestion.

Increased Safety & Security

Recreational Enjoyment

Time-Saving Convenience

Pet Wellbeing Life Gold for Cats is a premium, broad-spectrum immune and antioxidant formula designed for comprehensive long-term support, combining vitamins, antioxidants and fatty acids in a palatable format. It stands apart from single-ingredient lysine supplements by offering a more holistic nutrient profile and typically higher per-unit cost, positioned for owners who prefer an all-in-one, higher-end regimen rather than piecemeal additions. Technically and financially, Life Gold targets customers willing to invest in a consolidated, high-quality maintenance formula rather than basic lysine alone.

  • Broad-spectrum support

  • Antioxidant-rich formula

  • Drop-and-go mix

  • Comprehensive multi-nutrient formula combining antioxidants, essential fatty acids, and probiotics to support immunity and digestion.

  • Designed for daily maintenance to promote overall health, skin and coat condition, and gut balance.

  • Broad-spectrum support

  • Antioxidant-rich formula

  • Drop-and-go mix

  • Comprehensive multi-nutrient formula combining antioxidants, essential fatty acids, and probiotics to support immunity and digestion.

  • Designed for daily maintenance to promote overall health, skin and coat condition, and gut balance.

Order Now
From 51.97$

What the Research Says About Immune and Antioxidant Support for Cats

Scientific research on immune and antioxidant supplements for cats includes controlled trials, observational studies, and laboratory research. Evidence supports the role of antioxidants and select immune modulators in reducing markers of oxidative stress and supporting immune cell function, but results can vary by ingredient, dose, and the specific health context of the cat. Some ingredients, like L-lysine, have mixed clinical evidence for reducing herpesvirus symptoms in cats; others, such as beta-glucans and vitamins E and C, show more consistent immunomodulatory or antioxidant effects across multiple species. Because high-quality feline-specific trials are still limited in certain areas, it is important to interpret study results carefully, prefer products with transparent testing, and consult a veterinarian when choosing a regimen.

Antioxidants (vitamin E, vitamin C analogs) help neutralize free radicals and have been shown in animal studies to reduce oxidative stress markers and support overall cellular health.

Beta-glucans are biologically active polysaccharides that have demonstrated immune-modulating effects in multiple species by enhancing innate immune responses and supporting macrophage activity.

L-lysine has been studied for feline herpesvirus (FHV-1) management; clinical results are mixed—some trials report reduced clinical signs in certain populations, while others find minimal benefit—so veterinarian guidance is recommended.

Clinical evidence specific to cats is growing but still smaller in scale than for humans or food-production animals; look for randomized controlled trials, peer-reviewed publications, and manufacturer transparency about study design and outcomes.

Quality control matters: third-party testing, Good Manufacturing Practice (GMP) production, and clear dosing instructions reduce variability and increase the likelihood that a supplement will deliver expected benefits.

In the Canadian context, immune and antioxidant supplements that combine quality ingredients and clear veterinary guidance are the most useful for everyday pet care. The top options on this page include NaturVet Lysine Plus Immune Support for Cats, Zesty Paws Core Elements Daily Immune Support for Cats, VetriScience Vetri Lysine Plus, NOW Pets L-Lysine for Cats, and Pet Wellbeing Life Gold for Cats. For a balanced, veterinarian-formulated choice that often stands out for product quality and formulation transparency, VetriScience Vetri Lysine Plus is a strong pick among these five. We hope you found what you were looking for — use the site search or filters to refine by ingredient, format, or availability in Canada if you want to narrow or expand your options.

Discover More
  • Multivitamins and Mineral Supplements for Cats
  • Digestive and Probiotic Supplements for Cats
  • Life Stage Formulas for Cats
  • Behavioral and Calming Supplements for Cats
  • Cardiac and Taurine Support for Cats
  • Herbal and Botanical Supplements for Cats

Copyright © 2025 InceptionAi Inc.

Trademark Policy

Articles

About Us

Contact Us

Careers

Sitemap