Zymox Otic Pet Ear Treatment
Zymox Otic Pet Ear Treatment is best-in-class for dogs with recurring or active ear infections thanks to its enzymatic LP3 system that targets bacteria, yeast, and fungi without relying on traditional antibiotics. It tends to be pricier than routine cleaners on this list but often reduces the need for prescription drugs and vet follow-ups, making it a technically stronger option for infection control compared with foaming cleansers and wipes. For owners focused on resolving stubborn infections, Zymox offers a clinically oriented alternative to maintenance products like TropiClean wipes or Burt's Bees gentle cleansers.
Enzyme-powered bio-ninjas
Rapid itch relief
Enzyme-powered bio-ninjas
Rapid itch relief
Review Summary
"Users frequently report rapid improvement in chronic ear infections and reduced itching; it's praised as very effective though pricier than many alternatives and some dogs resist application."
Vet-approved champion
LP3 enzymatic system helps control bacteria, yeast, and fungi in the ear
Vet-approved champion
LP3 enzymatic system helps control bacteria, yeast, and fungi in the ear
Increased Safety & Security
Time-Saving Convenience
Zymox Otic Pet Ear Treatment is best-in-class for dogs with recurring or active ear infections thanks to its enzymatic LP3 system that targets bacteria, yeast, and fungi without relying on traditional antibiotics. It tends to be pricier than routine cleaners on this list but often reduces the need for prescription drugs and vet follow-ups, making it a technically stronger option for infection control compared with foaming cleansers and wipes. For owners focused on resolving stubborn infections, Zymox offers a clinically oriented alternative to maintenance products like TropiClean wipes or Burt's Bees gentle cleansers.
Enzyme-powered bio-ninjas
Rapid itch relief
Vet-approved champion
LP3 enzymatic system helps control bacteria, yeast, and fungi in the ear
OTC topical formula designed for short-course treatment of otic infections
Enzyme-powered bio-ninjas
Rapid itch relief
Vet-approved champion
LP3 enzymatic system helps control bacteria, yeast, and fungi in the ear
OTC topical formula designed for short-course treatment of otic infections
Epi-Otic Advanced Ear Cleaner
Epi-Otic Advanced is a market-leading veterinary ear cleanser prized for its gentle, non-irritating, foaming formula and widespread clinical use, making it a go-to choice for routine cleans and pre-treatment prep. While it is not marketed as an antimicrobial cure like Zymox, its strong debris- and wax-removal performance and cost-effective multi-use bottles give it a technical and financial advantage for regular vet-recommended maintenance. Compared with botanical or wipe-based products on this list, Epi-Otic strikes a balance between clinical effectiveness and everyday affordability for dog ear care.
Gentle non-irritating
Deep cleansing action
Gentle non-irritating
Deep cleansing action
Review Summary
"Vets and owners like it for thorough, non‑irritating cleaning and reliable odor control; a minority note it can sting if the ear is raw or has open wounds."
Clinic-grade calm
Alcohol-free, non-irritating cleanser that helps remove wax and debris
Clinic-grade calm
Alcohol-free, non-irritating cleanser that helps remove wax and debris
Increased Safety & Security
Time-Saving Convenience
Epi-Otic Advanced is a market-leading veterinary ear cleanser prized for its gentle, non-irritating, foaming formula and widespread clinical use, making it a go-to choice for routine cleans and pre-treatment prep. While it is not marketed as an antimicrobial cure like Zymox, its strong debris- and wax-removal performance and cost-effective multi-use bottles give it a technical and financial advantage for regular vet-recommended maintenance. Compared with botanical or wipe-based products on this list, Epi-Otic strikes a balance between clinical effectiveness and everyday affordability for dog ear care.
Gentle non-irritating
Deep cleansing action
Clinic-grade calm
Alcohol-free, non-irritating cleanser that helps remove wax and debris
Acidic formulation helps restore and maintain healthy ear pH
Gentle non-irritating
Deep cleansing action
Clinic-grade calm
Alcohol-free, non-irritating cleanser that helps remove wax and debris
Acidic formulation helps restore and maintain healthy ear pH
$18-28 CAD
Vet's Best Ear Relief Wash
Vet's Best Ear Relief Wash positions itself as a plant-derived, gentle ear cleaner that appeals to owners seeking natural ingredient profiles and soothing action for sensitive dogs. It is generally more affordable than specialty enzymatic treatments and offers a softer option than strong clinical cleaners, though it may be less effective for active infections than Zymox or professional vet products. As a middle-ground solution, Vet's Best is a budget-friendly maintenance choice that complements stronger antimicrobials and is preferable to wipes when a deeper rinse is needed.
Herbal soothing hug
Odor-banishing botanicals
Herbal soothing hug
Odor-banishing botanicals
Review Summary
"Owners appreciate the natural, gentle formula and pleasant scent for routine maintenance, but many say it's less effective on heavy wax buildup or active infections."
Pup-friendly scent
Plant-based cleansers with soothing ingredients like aloe and vitamin E
Pup-friendly scent
Plant-based cleansers with soothing ingredients like aloe and vitamin E
Increased Safety & Security
Time-Saving Convenience
Vet's Best Ear Relief Wash positions itself as a plant-derived, gentle ear cleaner that appeals to owners seeking natural ingredient profiles and soothing action for sensitive dogs. It is generally more affordable than specialty enzymatic treatments and offers a softer option than strong clinical cleaners, though it may be less effective for active infections than Zymox or professional vet products. As a middle-ground solution, Vet's Best is a budget-friendly maintenance choice that complements stronger antimicrobials and is preferable to wipes when a deeper rinse is needed.
Herbal soothing hug
Odor-banishing botanicals
Pup-friendly scent
Plant-based cleansers with soothing ingredients like aloe and vitamin E
Formulated to soothe irritation and help remove dirt and wax buildup
Herbal soothing hug
Odor-banishing botanicals
Pup-friendly scent
Plant-based cleansers with soothing ingredients like aloe and vitamin E
Formulated to soothe irritation and help remove dirt and wax buildup
$12-20 CAD
TropiClean Ear Cleaning Wipes
TropiClean Ear Cleaning Wipes are a convenience-focused, low-cost option ideal for daily upkeep, quick odor control, and on-the-go cleanings between more thorough washes. They are not a substitute for enzymatic or vet-grade liquid treatments for infections, but their per-use affordability and portability make them the most practical choice for routine spot cleaning compared with bottled cleaners. For owners who prioritize simplicity and travel-ready care, TropiClean wipes complement clinical products like Epi-Otic or Zymox rather than replacing them.
Pocket-ready cleanup
No-rinse convenience
Pocket-ready cleanup
No-rinse convenience
Review Summary
"Convenient and effective for surface debris and daily upkeep with most dogs tolerating them well; however, they don't replace liquid cleaners for deep cleaning and some report a slight residue."
Tropical scent boost
Pre-moistened wipes for convenient, single-step ear cleaning on the go
Tropical scent boost
Pre-moistened wipes for convenient, single-step ear cleaning on the go
Time-Saving Convenience
TropiClean Ear Cleaning Wipes are a convenience-focused, low-cost option ideal for daily upkeep, quick odor control, and on-the-go cleanings between more thorough washes. They are not a substitute for enzymatic or vet-grade liquid treatments for infections, but their per-use affordability and portability make them the most practical choice for routine spot cleaning compared with bottled cleaners. For owners who prioritize simplicity and travel-ready care, TropiClean wipes complement clinical products like Epi-Otic or Zymox rather than replacing them.
Pocket-ready cleanup
No-rinse convenience
Tropical scent boost
Pre-moistened wipes for convenient, single-step ear cleaning on the go
Helps remove surface wax and neutralize odor without rinsing
Pocket-ready cleanup
No-rinse convenience
Tropical scent boost
Pre-moistened wipes for convenient, single-step ear cleaning on the go
Helps remove surface wax and neutralize odor without rinsing
Burt's Bees Care Plus+ Ear Cleaner
Burt's Bees Care Plus+ Ear Cleaner brings a soap-free, naturally inclined formulation from a well-known personal-care brand, offering gentle cleaning and good value for regular home use. It sits between botanical washes like Vet's Best and clinical rinses like Epi-Otic: gentler than vet-grade antiseptics but more substantial than single-use wipes, which makes it a solid everyday option for dogs with mild sensitivity. Financially it competes well on price-per-use while providing a recognizable natural-brand assurance for owners focused on gentler ear care.
Gentle natural formula
Alcohol-free clean
Gentle natural formula
Alcohol-free clean
Review Summary
"Popular for a gentle, natural formula that cleans routine buildup without harsh chemicals, but several reviewers say it's not strong enough to clear persistent infections."
Bee-approved gentle
Made with mostly natural ingredients and a pH-balanced, gentle formula
Bee-approved gentle
Made with mostly natural ingredients and a pH-balanced, gentle formula
Increased Safety & Security
Time-Saving Convenience
Burt's Bees Care Plus+ Ear Cleaner brings a soap-free, naturally inclined formulation from a well-known personal-care brand, offering gentle cleaning and good value for regular home use. It sits between botanical washes like Vet's Best and clinical rinses like Epi-Otic: gentler than vet-grade antiseptics but more substantial than single-use wipes, which makes it a solid everyday option for dogs with mild sensitivity. Financially it competes well on price-per-use while providing a recognizable natural-brand assurance for owners focused on gentler ear care.
Gentle natural formula
Alcohol-free clean
Bee-approved gentle
Made with mostly natural ingredients and a pH-balanced, gentle formula
Designed to lift dirt and wax while minimizing irritation
Gentle natural formula
Alcohol-free clean
Bee-approved gentle
Made with mostly natural ingredients and a pH-balanced, gentle formula
Designed to lift dirt and wax while minimizing irritation