Atenolol 25mg Tablets
Atenolol 25mg holds a best-in-class position for small-breed dogs because its lower tablet strength enables precise, titratable dosing for chronic management of hypertension and some cardiomyopathies. As a beta-1 selective agent it tends to have less bronchial and central nervous system penetration than non-selective propranolol products, and it is often more cost-effective per milligram for long-term therapy compared with higher-strength tablets that require splitting. Compared with sotalol, it lacks Class III antiarrhythmic effects but offers a simpler safety profile that can reduce monitoring costs in suitable patients.
Slows heart rate
Low-dose precision
Slows heart rate
Low-dose precision
Review Summary
"Owners generally report atenolol 25mg reliably lowers heart rate and improves symptoms in small dogs with minimal side effects; a few users mention mild lethargy or reduced appetite but praise its affordability and ease of dosing."
Pup-friendly portion
Selective beta-1 blocker commonly used for canine hypertension and some arrhythmias.
Pup-friendly portion
Selective beta-1 blocker commonly used for canine hypertension and some arrhythmias.
Increased Safety & Security
Time-Saving Convenience
Atenolol 25mg holds a best-in-class position for small-breed dogs because its lower tablet strength enables precise, titratable dosing for chronic management of hypertension and some cardiomyopathies. As a beta-1 selective agent it tends to have less bronchial and central nervous system penetration than non-selective propranolol products, and it is often more cost-effective per milligram for long-term therapy compared with higher-strength tablets that require splitting. Compared with sotalol, it lacks Class III antiarrhythmic effects but offers a simpler safety profile that can reduce monitoring costs in suitable patients.
Slows heart rate
Low-dose precision
Pup-friendly portion
Selective beta-1 blocker commonly used for canine hypertension and some arrhythmias.
Low-dose tablet ideal for small dogs where dose titration is needed.
Slows heart rate
Low-dose precision
Pup-friendly portion
Selective beta-1 blocker commonly used for canine hypertension and some arrhythmias.
Low-dose tablet ideal for small dogs where dose titration is needed.
$10-30 CAD
Atenolol 50mg Tablets
Atenolol 50mg is positioned as the market leader for medium-to-large dogs where fewer tablets per dose improves compliance and lowers dispensing costs, offering a competitive price-per-tablet advantage over multiple low-strength tablets. It preserves the beta-1 selectivity benefits of atenolol—reduced bronchial side effects versus propranolol—while trading some dosing flexibility for simpler administration. Compared with sotalol, it remains a more economical option when antiarrhythmic Class III action is not required, though it may necessitate tablet division in smaller patients.
Stronger dose control
Longer steady effect
Stronger dose control
Longer steady effect
Review Summary
"Atenolol 50mg receives similar feedback for larger dogs — effective at controlling cardiac signs and tolerated well overall, though some reviewers note tablet size and occasional mild lethargy as drawbacks."
Handles big pups
Provides a higher-strength option for medium to large dogs with cardiac conditions.
Handles big pups
Provides a higher-strength option for medium to large dogs with cardiac conditions.
Increased Safety & Security
Time-Saving Convenience
Atenolol 50mg is positioned as the market leader for medium-to-large dogs where fewer tablets per dose improves compliance and lowers dispensing costs, offering a competitive price-per-tablet advantage over multiple low-strength tablets. It preserves the beta-1 selectivity benefits of atenolol—reduced bronchial side effects versus propranolol—while trading some dosing flexibility for simpler administration. Compared with sotalol, it remains a more economical option when antiarrhythmic Class III action is not required, though it may necessitate tablet division in smaller patients.
Stronger dose control
Longer steady effect
Handles big pups
Provides a higher-strength option for medium to large dogs with cardiac conditions.
Selective beta-1 activity helps reduce cardiac workload with fewer respiratory side effects.
Stronger dose control
Longer steady effect
Handles big pups
Provides a higher-strength option for medium to large dogs with cardiac conditions.
Selective beta-1 activity helps reduce cardiac workload with fewer respiratory side effects.
$15-40 CAD
Propranolol 10mg Tablets
Propranolol 10mg is a commonly used small-dose, non-selective beta blocker favored when clinicians require both peripheral and central beta blockade in small dogs, and its low strength facilitates fine dosing adjustments. Its higher lipophilicity relative to atenolol provides different therapeutic effects in some arrhythmic or stress-related indications, though this can also increase the potential for central side effects and monitoring needs. Financially it is typically low-cost per tablet, making it a practical choice for short-term or adjunctive therapy compared with the more specialized and expensive sotalol.
Calms adrenaline spikes
Small tablet size
Calms adrenaline spikes
Small tablet size
Review Summary
"Propranolol 10mg is reported effective for certain arrhythmias and situational anxiety, but more users describe gastrointestinal upset, lethargy, or variable responses compared with selective beta blockers."
Great for noise storms
Non-selective beta blocker used for arrhythmias and some cardiac-related anxiety in dogs.
Great for noise storms
Non-selective beta blocker used for arrhythmias and some cardiac-related anxiety in dogs.
Increased Safety & Security
Time-Saving Convenience
Propranolol 10mg is a commonly used small-dose, non-selective beta blocker favored when clinicians require both peripheral and central beta blockade in small dogs, and its low strength facilitates fine dosing adjustments. Its higher lipophilicity relative to atenolol provides different therapeutic effects in some arrhythmic or stress-related indications, though this can also increase the potential for central side effects and monitoring needs. Financially it is typically low-cost per tablet, making it a practical choice for short-term or adjunctive therapy compared with the more specialized and expensive sotalol.
Calms adrenaline spikes
Small tablet size
Great for noise storms
Non-selective beta blocker used for arrhythmias and some cardiac-related anxiety in dogs.
Lower dose tablet suitable for fine titration in small breeds or when central nervous system penetration is desired.
Calms adrenaline spikes
Small tablet size
Great for noise storms
Non-selective beta blocker used for arrhythmias and some cardiac-related anxiety in dogs.
Lower dose tablet suitable for fine titration in small breeds or when central nervous system penetration is desired.
$8-25 CAD
Propranolol 40mg Tablets
Propranolol 40mg targets larger patients or high-dose protocols where tablet economy and reduced pill burden are priorities, offering a lower cost-per-dose for clinics treating large-breed dogs. As a non-selective beta blocker it shares the broader physiological effects of propranolol 10mg but with less dosing granularity, which can make it less suitable for small or dose-sensitive patients compared with atenolol 25mg. While generally less expensive than sotalol, it lacks sotalol’s Class III antiarrhythmic capability and therefore is chosen when broad beta blockade rather than rhythm-specific therapy is desired.
Robust anxiety control
Versatile dosing option
Robust anxiety control
Versatile dosing option
Review Summary
"Propranolol 40mg gives comparable efficacy for larger dogs but carries the same higher rate of side effects and mixed responses; reviewers often note the need for close monitoring and dose adjustments."
Road-trip ready
Higher-strength non-selective beta blocker for medium to large dogs with arrhythmias.
Road-trip ready
Higher-strength non-selective beta blocker for medium to large dogs with arrhythmias.
Increased Safety & Security
Time-Saving Convenience
Propranolol 40mg targets larger patients or high-dose protocols where tablet economy and reduced pill burden are priorities, offering a lower cost-per-dose for clinics treating large-breed dogs. As a non-selective beta blocker it shares the broader physiological effects of propranolol 10mg but with less dosing granularity, which can make it less suitable for small or dose-sensitive patients compared with atenolol 25mg. While generally less expensive than sotalol, it lacks sotalol’s Class III antiarrhythmic capability and therefore is chosen when broad beta blockade rather than rhythm-specific therapy is desired.
Robust anxiety control
Versatile dosing option
Road-trip ready
Higher-strength non-selective beta blocker for medium to large dogs with arrhythmias.
Effective for systemic beta blockade but may affect airways and glucose regulation.
Robust anxiety control
Versatile dosing option
Road-trip ready
Higher-strength non-selective beta blocker for medium to large dogs with arrhythmias.
Effective for systemic beta blockade but may affect airways and glucose regulation.
$12-35 CAD
Sotalol 80mg Tablets
Sotalol 80mg is the market leader for canine ventricular arrhythmia management because it combines non-selective beta blockade with Class III potassium-channel blockade, providing rhythm-control advantages that atenolol and propranolol do not. This dual mechanism carries higher monitoring requirements (ECG and renal assessment) and generally higher cost, but it can be clinically and economically justified for dogs with life‑threatening or refractory arrhythmias where fewer hospital interventions offset drug expense. Compared with the atenolol and propranolol options, sotalol is the technical choice when antiarrhythmic potency is the primary therapeutic goal rather than simple rate control or long-term hypertension management.
Anti-arrhythmic power
Dual beta-blocking
Anti-arrhythmic power
Dual beta-blocking
Review Summary
"Sotalol 80mg is frequently praised for strong antiarrhythmic effects in dogs and noticeable clinical improvement, though many owners mention higher cost, need for ECG/monitoring, and occasional adverse effects."
Guard dog mode
Class III antiarrhythmic with non-selective beta-blocking properties, commonly used for ventricular arrhythmias in dogs.
Guard dog mode
Class III antiarrhythmic with non-selective beta-blocking properties, commonly used for ventricular arrhythmias in dogs.
Increased Safety & Security
Time-Saving Convenience
Sotalol 80mg is the market leader for canine ventricular arrhythmia management because it combines non-selective beta blockade with Class III potassium-channel blockade, providing rhythm-control advantages that atenolol and propranolol do not. This dual mechanism carries higher monitoring requirements (ECG and renal assessment) and generally higher cost, but it can be clinically and economically justified for dogs with life‑threatening or refractory arrhythmias where fewer hospital interventions offset drug expense. Compared with the atenolol and propranolol options, sotalol is the technical choice when antiarrhythmic potency is the primary therapeutic goal rather than simple rate control or long-term hypertension management.
Anti-arrhythmic power
Dual beta-blocking
Guard dog mode
Class III antiarrhythmic with non-selective beta-blocking properties, commonly used for ventricular arrhythmias in dogs.
Requires ECG monitoring and dose adjustments because of proarrhythmic risk and renal excretion.
Anti-arrhythmic power
Dual beta-blocking
Guard dog mode
Class III antiarrhythmic with non-selective beta-blocking properties, commonly used for ventricular arrhythmias in dogs.
Requires ECG monitoring and dose adjustments because of proarrhythmic risk and renal excretion.
$40-120 CAD