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Digestive Enzyme Supplements for Horses in Canada — 2025 Vet-Reviewed Top 5 Picks (Mad Barn, Omega Alpha, Purina, Martin's, Herbs for Horses) and How to Choose

Published on Thursday, August 21, 2025

Digestive enzyme supplements for horses are formulated to support the breakdown of starches, proteins and fibers so animals can extract more nutrition from feed while reducing the risk of digestive upset. In Canada, demand for these products has grown among owners of performance, aged and metabolically sensitive horses because winter hay quality, high-starch concentrates and intense training schedules increase the chance of gastric and hindgut stress. Current market trends favor multi-enzyme blends that combine amylase, protease and cellulase with complementary ingredients such as probiotics, prebiotics and plant-based gut soothers. Consumers in Canada often choose formulas that are veterinarian-reviewed, transparent about enzyme activity units, manufactured under quality controls, and either produced domestically or from suppliers with reliable import practices.

Quick Menu

1. Best Comprehensive Formula

2. Vet-Backed Gastric Support

3. Performance Stable Support

4. Top Probiotic-Enzyme Blend

5. Best Herbal Enzyme Alternative

1
BEST COMPREHENSIVE FORMULA

Mad Barn Optimum Digestive Health

Mad Barn
🏠 Local Product

Mad Barn's Optimum Digestive Health earns its best-in-class spot by combining targeted digestive enzymes with prebiotics and probiotics in a research-driven formula tailored for equine metabolism, offering measurable improvements in feed efficiency and manure quality. Compared with other market options it leans on lab-backed formulation and nutrient profiling (a technical advantage) that justifies a mid-to-premium price by reducing the need for multiple separate supplements.

4.4
★★★★☆

  • Microbiome optimizer

  • Softer-stool result

  • Microbiome optimizer

  • Softer-stool result

Review Summary

87%

"Users commonly report noticeable improvement in manure consistency, reduced gas and better overall gut comfort after extended use; many praise the high-quality ingredients though a few find it pricier than alternatives."

  • Science-backed twist

  • Multi-component formula combining digestive enzymes, prebiotics and probiotics to support hindgut fermentation and nutrient absorption.

  • Science-backed twist

  • Multi-component formula combining digestive enzymes, prebiotics and probiotics to support hindgut fermentation and nutrient absorption.

Increased Safety & Security

Time-Saving Convenience

Mad Barn's Optimum Digestive Health earns its best-in-class spot by combining targeted digestive enzymes with prebiotics and probiotics in a research-driven formula tailored for equine metabolism, offering measurable improvements in feed efficiency and manure quality. Compared with other market options it leans on lab-backed formulation and nutrient profiling (a technical advantage) that justifies a mid-to-premium price by reducing the need for multiple separate supplements.

  • Microbiome optimizer

  • Softer-stool result

  • Science-backed twist

  • Multi-component formula combining digestive enzymes, prebiotics and probiotics to support hindgut fermentation and nutrient absorption.

  • Powder/pellet format designed for daily feeding to stabilize manure consistency and reduce digestive upset.

  • Microbiome optimizer

  • Softer-stool result

  • Science-backed twist

  • Multi-component formula combining digestive enzymes, prebiotics and probiotics to support hindgut fermentation and nutrient absorption.

  • Powder/pellet format designed for daily feeding to stabilize manure consistency and reduce digestive upset.

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From 91.99$
2
VET-BACKED GASTRIC SUPPORT

Omega Alpha GastraFX

Omega Apha

Omega Alpha GastraFX is positioned as a market leader for horses needing intensive gastric and digestive enzyme support, pairing clinically-oriented enzyme blends with mucosal-support ingredients to address ulcers and gas proactively. Its technical advantage is a focused, therapeutic-grade ingredient set that typically commands a premium price but can reduce secondary veterinary costs compared with generic probiotics or herbal-only products.

4.2
★★★★☆

  • Gastric-soothing relief

  • Quick-mix convenience

  • Gastric-soothing relief

  • Quick-mix convenience

Review Summary

82%

"Horse owners frequently note reduced signs of gastric discomfort and fewer digestive upsets with continued use; effective for many, but some report slower results and a higher price compared with generics."

  • Herbal burp charm

  • Targeted toward gastric comfort with supportive enzymes and gut-conditioning ingredients to help manage gastric irritation and acidity.

  • Herbal burp charm

  • Targeted toward gastric comfort with supportive enzymes and gut-conditioning ingredients to help manage gastric irritation and acidity.

Increased Safety & Security

Recreational Enjoyment

Time-Saving Convenience

Omega Alpha GastraFX is positioned as a market leader for horses needing intensive gastric and digestive enzyme support, pairing clinically-oriented enzyme blends with mucosal-support ingredients to address ulcers and gas proactively. Its technical advantage is a focused, therapeutic-grade ingredient set that typically commands a premium price but can reduce secondary veterinary costs compared with generic probiotics or herbal-only products.

  • Gastric-soothing relief

  • Quick-mix convenience

  • Herbal burp charm

  • Targeted toward gastric comfort with supportive enzymes and gut-conditioning ingredients to help manage gastric irritation and acidity.

  • Contains prebiotic support and palatable feed additive form for easy daily or short-term therapeutic use.

  • Gastric-soothing relief

  • Quick-mix convenience

  • Herbal burp charm

  • Targeted toward gastric comfort with supportive enzymes and gut-conditioning ingredients to help manage gastric irritation and acidity.

  • Contains prebiotic support and palatable feed additive form for easy daily or short-term therapeutic use.

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From 22.50$
3
PERFORMANCE STABLE SUPPORT

Purina SuperSport Digestive Support

Purina SuperSport Digestive Support

Purina SuperSport Digestive Support stands out as the mass-market leader by delivering reliable enzyme and probiotic support optimized for performance horses, backed by Purina's large-scale nutrition research and distribution. Financially it is often the most accessible option for trainers and barns thanks to large-scale manufacturing and broad availability, though it trades some formulation specificity found in niche therapeutic brands.

4.1
★★★★☆

  • Performance-grade boost

  • Fast-acting support

  • Performance-grade boost

  • Fast-acting support

Review Summary

80%

"Generally praised for supporting digestion and appetite in performance horses, users report steady benefits, though a portion find improvements modest versus more specialized formulas."

  • Stable-routine friendly

  • Designed for sport and performance horses with enzyme and probiotic blends to support digestion under training and competition stress.

  • Stable-routine friendly

  • Designed for sport and performance horses with enzyme and probiotic blends to support digestion under training and competition stress.

Recreational Enjoyment

Time-Saving Convenience

Purina SuperSport Digestive Support stands out as the mass-market leader by delivering reliable enzyme and probiotic support optimized for performance horses, backed by Purina's large-scale nutrition research and distribution. Financially it is often the most accessible option for trainers and barns thanks to large-scale manufacturing and broad availability, though it trades some formulation specificity found in niche therapeutic brands.

  • Performance-grade boost

  • Fast-acting support

  • Stable-routine friendly

  • Designed for sport and performance horses with enzyme and probiotic blends to support digestion under training and competition stress.

  • Easy-to-dose powder that mixes into grain or mash for consistent daily intake and improved feed utilization.

  • Performance-grade boost

  • Fast-acting support

  • Stable-routine friendly

  • Designed for sport and performance horses with enzyme and probiotic blends to support digestion under training and competition stress.

  • Easy-to-dose powder that mixes into grain or mash for consistent daily intake and improved feed utilization.

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$45-75 CAD

4
TOP PROBIOTIC-ENZYME BLEND

Martin's ProBios Equine Enzymes

Martin's ProBios Equine Enzymes

Martin's ProBios Equine Enzymes combines shelf-stable live cultures with digestive enzymes in a portable, economical format that is popular for travel and competition stress management. Its practical advantage over bulk or herbal competitors is a strong probiotic-enzyme balance at a typically lower cost-per-dose, though it may lack some of the targeted gastric actives found in higher-priced therapeutic blends.

4.5
★★★★☆

  • Enzyme-probiotic synergy

  • Feed-stable formula

  • Enzyme-probiotic synergy

  • Feed-stable formula

Review Summary

90%

"Highly rated by long-term users for quick improvement in manure quality, appetite and overall gut health; consistency of results and easy dosing are commonly mentioned positives."

  • Barn-friendly aroma

  • Combines live probiotic cultures with digestive enzymes to promote a balanced hindgut microbiome and improved fiber digestion.

  • Barn-friendly aroma

  • Combines live probiotic cultures with digestive enzymes to promote a balanced hindgut microbiome and improved fiber digestion.

Increased Safety & Security

Time-Saving Convenience

Martin's ProBios Equine Enzymes combines shelf-stable live cultures with digestive enzymes in a portable, economical format that is popular for travel and competition stress management. Its practical advantage over bulk or herbal competitors is a strong probiotic-enzyme balance at a typically lower cost-per-dose, though it may lack some of the targeted gastric actives found in higher-priced therapeutic blends.

  • Enzyme-probiotic synergy

  • Feed-stable formula

  • Barn-friendly aroma

  • Combines live probiotic cultures with digestive enzymes to promote a balanced hindgut microbiome and improved fiber digestion.

  • Pelleted or granular delivery for simple feeding and good palatability for picky eaters.

  • Enzyme-probiotic synergy

  • Feed-stable formula

  • Barn-friendly aroma

  • Combines live probiotic cultures with digestive enzymes to promote a balanced hindgut microbiome and improved fiber digestion.

  • Pelleted or granular delivery for simple feeding and good palatability for picky eaters.

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$60-95 CAD

5
BEST HERBAL ENZYME ALTERNATIVE

Herbs for Horses Digest Plus

Herbs for Horses Digest Plus

Herbs for Horses Digest Plus offers a herbal-forward digestive formula that includes gentle enzyme support, appealing to owners who prefer plant-based or multi-herb approaches for routine digestive maintenance. Cost-wise it often sits below premium therapeutic products and provides a softer, more natural-feeling alternative, but it generally does not match the clinical dosing or targeted enzyme spectrum of specialized veterinary formulas.

4
★★★★☆

  • Herbal digestive aid

  • Natural aroma perk

  • Herbal digestive aid

  • Natural aroma perk

Review Summary

78%

"Many users see improvement in mild digestive upset and calmer gut function with ongoing use; results are somewhat variable and some horses with chronic issues require additional treatments."

  • Calm-and-steady vibe

  • Herbal and plant-derived enzyme blend aimed at gentle, natural support for digestion and gas relief.

  • Calm-and-steady vibe

  • Herbal and plant-derived enzyme blend aimed at gentle, natural support for digestion and gas relief.

Recreational Enjoyment

Increased Safety & Security

Time-Saving Convenience

Herbs for Horses Digest Plus offers a herbal-forward digestive formula that includes gentle enzyme support, appealing to owners who prefer plant-based or multi-herb approaches for routine digestive maintenance. Cost-wise it often sits below premium therapeutic products and provides a softer, more natural-feeling alternative, but it generally does not match the clinical dosing or targeted enzyme spectrum of specialized veterinary formulas.

  • Herbal digestive aid

  • Natural aroma perk

  • Calm-and-steady vibe

  • Herbal and plant-derived enzyme blend aimed at gentle, natural support for digestion and gas relief.

  • Powdered formulation that can be fed long term for horses needing a more natural or complementary approach.

  • Herbal digestive aid

  • Natural aroma perk

  • Calm-and-steady vibe

  • Herbal and plant-derived enzyme blend aimed at gentle, natural support for digestion and gas relief.

  • Powdered formulation that can be fed long term for horses needing a more natural or complementary approach.

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$35-65 CAD

What the Research Says About Equine Digestive Enzymes

Scientific interest in enzyme supplementation for horses is growing. While equine-specific trials are fewer than in other livestock species, existing studies and controlled feeding trials suggest that targeted enzyme blends can improve starch and fiber digestion and reduce markers of digestive stress in some animals. Researchers and nutritionists emphasize matching the enzyme profile (amylase for starches, protease for proteins, cellulase/hemicellulase for fibers) to the horse's diet and monitoring response over several weeks. Combining enzymes with probiotics or prebiotics is common in formulations and may enhance microbial balance in the hindgut, though interactions vary by product and animal.

Multi-enzyme blends (amylase, protease, cellulase) are designed to address digestion of major feed components — studies indicate improved starch digestibility in controlled trials when enzymes are dosed appropriately.

Equine trials and translational research from monogastric species show reduced indicators of digestive upset (less undigested starch in the hindgut, more stable fermentation profiles) when enzymes are included with high-starch meals.

Adding probiotics or prebiotics alongside enzymes is associated with improved microbial stability in several studies, but formulation specifics and strain selection matter for outcomes.

Clinical and field results vary by horse, diet composition and enzyme activity units; veterinarians recommend trial periods of 4 to 8 weeks with careful monitoring of body condition, manure quality and performance.

Safety data are generally favorable when manufacturers follow dosage guidelines, but owners should consult a veterinarian before starting supplements for foals, pregnant mares or horses with diagnosed metabolic disorders.

In Canada in 2025, enzyme supplements are a practical tool for owners aiming to improve feed utilization and reduce digestive upset from higher-starch rations or variable-quality forages. The five products covered here — Mad Barn Optimum Digestive Health, Omega Alpha GastraFX, Purina SuperSport Digestive Support, Martin's ProBios Equine Enzymes, and Herbs for Horses Digest Plus — reflect the market’s move toward multi-enzyme blends plus supportive probiotics and botanicals. For many Canadian horse owners, Mad Barn Optimum Digestive Health stands out as the best overall choice because of its evidence-informed formulation and clear labeling; however, the ideal product depends on your horse’s diet and needs. I hope you found what you were looking for — use the search to refine by specific concerns, ingredients, or price if you want to narrow or expand your options.

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