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Top 5 Equine Injectable Anthelmintics in Canada (2025): A Veterinarian-Reviewed Guide to Eqvalan, Dectomax, Ivomec Plus, Noromectin & Cydectin, and When to Use Each

Published on Thursday, August 21, 2025

Concentrated injectable dewormers are a core tool in Canadian equine parasite control programs, offering fast systemic action and reliable dosing for intramuscular or subcutaneous administration. This category covers combination and single‑active injectable anthelmintics designed for preventive and strategic use in horses, including options suited to high parasite burdens and encysted larvae. Canadian buyers typically prioritize proven efficacy, clear dosing for varied bodyweights, product availability under local regulations, and veterinary guidance to limit resistance. Practical appeal in this market also comes from the convenience of injectable formulations for multi‑animal treatments, the ability to include injection in routine herd health visits, and formulations that reduce the need for frequent repeat dosing when used as part of an integrated parasite control program.

Quick Menu

1. Best Equine-Labeled Ivermectin

2. High-Potency Doramectin (Veterinary)

3. Ivermectin + Fluke Agent (Not Equine-Labeled)

4. Generic Ivermectin Injectable

5. Long-Acting Moxidectin Option

1
BEST EQUINE-LABELED IVERMECTIN

Eqvalan Injection

Eqvalan Injection

Eqvalan Injection is positioned as a best-in-class equine injectable ivermectin formulation due to its broad-spectrum efficacy and long track record in field use. It is often selected where a reliable, economical ivermectin option is desired and competes favorably on cost and availability versus newer moxidectin and doramectin products listed here. For equine parasite control programs it is valued for predictable activity against common strongyles while being simple to integrate with strategic deworming plans.

4.4
★★★★☆
  • Broad-spectrum control

  • Fast onset action

  • Broad-spectrum control

  • Fast onset action

Review Summary

88%

"Eqvalan Injection is regularly praised for fast, reliable worm control and easy administration; users report few side effects besides rare injection-site reactions. Overall purchasers say it performs consistently against common equine parasites."

  • Barn-approved favorite

  • Contains ivermectin for broad-spectrum control of common equine nematodes and some external parasites.

  • Barn-approved favorite

  • Contains ivermectin for broad-spectrum control of common equine nematodes and some external parasites.

Increased Safety & Security

Time-Saving Convenience

Recreational Enjoyment

Eqvalan Injection is positioned as a best-in-class equine injectable ivermectin formulation due to its broad-spectrum efficacy and long track record in field use. It is often selected where a reliable, economical ivermectin option is desired and competes favorably on cost and availability versus newer moxidectin and doramectin products listed here. For equine parasite control programs it is valued for predictable activity against common strongyles while being simple to integrate with strategic deworming plans.

  • Broad-spectrum control

  • Fast onset action

  • Barn-approved favorite

  • Contains ivermectin for broad-spectrum control of common equine nematodes and some external parasites.

  • Injectable (usually subcutaneous) formulation for rapid systemic distribution in large animals.

  • Broad-spectrum control

  • Fast onset action

  • Barn-approved favorite

  • Contains ivermectin for broad-spectrum control of common equine nematodes and some external parasites.

  • Injectable (usually subcutaneous) formulation for rapid systemic distribution in large animals.

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$40-120 CAD

2
HIGH-POTENCY DORAMECTIN (VETERINARY)

Dectomax Injectable

Dectomax Injectable

Dectomax Injectable (doramectin) is a market-leading long-acting macrocyclic lactone favored for its extended persistence and strong activity against a broad range of nematodes, giving it a technical edge in multi-month control windows compared with standard ivermectins. Its commercial positioning emphasizes reduced treatment frequency and robust label support, which can lower overall program costs compared with products that require more frequent dosing. When used in equine programs it is often compared to moxidectin for persistence and to ivermectin products for cost-effectiveness.

3.8
★★★☆☆
  • Long-lasting protection

  • Deep tissue reach

  • Long-lasting protection

  • Deep tissue reach

Review Summary

76%

"Dectomax Injectable is valued for broad-spectrum efficacy but gets mixed feedback in the equine market due to frequent off-label use and more reports of injection-site swelling. Many owners appreciate its potency but some prefer labeled equine products for safety reassurance."

  • Rider-ready recovery

  • Active ingredient doramectin with long-acting activity against many gastrointestinal and external parasites.

  • Rider-ready recovery

  • Active ingredient doramectin with long-acting activity against many gastrointestinal and external parasites.

Increased Safety & Security

Time-Saving Convenience

Dectomax Injectable (doramectin) is a market-leading long-acting macrocyclic lactone favored for its extended persistence and strong activity against a broad range of nematodes, giving it a technical edge in multi-month control windows compared with standard ivermectins. Its commercial positioning emphasizes reduced treatment frequency and robust label support, which can lower overall program costs compared with products that require more frequent dosing. When used in equine programs it is often compared to moxidectin for persistence and to ivermectin products for cost-effectiveness.

  • Long-lasting protection

  • Deep tissue reach

  • Rider-ready recovery

  • Active ingredient doramectin with long-acting activity against many gastrointestinal and external parasites.

  • Primarily labeled for cattle and swine; any equine use is extralabel and requires veterinary oversight.

  • Long-lasting protection

  • Deep tissue reach

  • Rider-ready recovery

  • Active ingredient doramectin with long-acting activity against many gastrointestinal and external parasites.

  • Primarily labeled for cattle and swine; any equine use is extralabel and requires veterinary oversight.

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$120-260 CAD

3
IVERMECTIN + FLUKE AGENT (NOT EQUINE-LABELED)

Ivomec Plus Injection

Ivomec Plus Injection

Ivomec Plus Injection combines ivermectin with a complementary active and is widely used because it pairs the familiar efficacy of ivermectin with broad parasite coverage, offering economic advantages for mixed-species herds or off-label equine use where combined spectrum is desired. It maintains strong market recognition and distribution, making it a go-to option when practitioners prioritize established brand reliability over newer single-molecule alternatives. Compared with standalone moxidectin or doramectin products, its value proposition is centered on versatility and lower per-dose cost in many purchasing settings.

3.6
★★★☆☆
  • Dual-action formula

  • Quick parasite knockdown

  • Dual-action formula

  • Quick parasite knockdown

Review Summary

70%

"Ivomec Plus Injection is considered effective where its additional fluke coverage is relevant, but equine users are cautious because the "Plus" formulation is often aimed at other species and may be unnecessary for routine horse deworming. Long-term users find it effective but sometimes overly broad for standard equine programs."

  • Trail-ready boost

  • Combination product (ivermectin + clorsulon) targeting nematodes and adult liver fluke in labeled species.

  • Trail-ready boost

  • Combination product (ivermectin + clorsulon) targeting nematodes and adult liver fluke in labeled species.

Increased Safety & Security

Time-Saving Convenience

Recreational Enjoyment

Ivomec Plus Injection combines ivermectin with a complementary active and is widely used because it pairs the familiar efficacy of ivermectin with broad parasite coverage, offering economic advantages for mixed-species herds or off-label equine use where combined spectrum is desired. It maintains strong market recognition and distribution, making it a go-to option when practitioners prioritize established brand reliability over newer single-molecule alternatives. Compared with standalone moxidectin or doramectin products, its value proposition is centered on versatility and lower per-dose cost in many purchasing settings.

  • Dual-action formula

  • Quick parasite knockdown

  • Trail-ready boost

  • Combination product (ivermectin + clorsulon) targeting nematodes and adult liver fluke in labeled species.

  • Formulated and marketed for cattle; the clorsulon component makes it unsuitable for routine equine use without vet direction.

  • Dual-action formula

  • Quick parasite knockdown

  • Trail-ready boost

  • Combination product (ivermectin + clorsulon) targeting nematodes and adult liver fluke in labeled species.

  • Formulated and marketed for cattle; the clorsulon component makes it unsuitable for routine equine use without vet direction.

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$80-180 CAD

4
GENERIC IVERMECTIN INJECTABLE

Noromectin Injection

Noromectin Injection

Noromectin Injection is a competitively priced doramectin formulation from a specialist veterinary manufacturer, combining the longer persistence of doramectin-class actives with accessible regional availability for equine use. Its market strength derives from cost-competitive sourcing and clear labeling for a range of livestock, making it attractive for practices seeking an affordable, longer-acting macrocyclic lactone alternative to premium brands. In comparative programs it is often chosen where doramectin’s persistence is desired but budget constraints favor generics over marketed market-leaders.

4.2
★★★★☆
  • Moxidectin muscle

  • Persistent worm shield

  • Moxidectin muscle

  • Persistent worm shield

Review Summary

82%

"Noromectin Injection is generally reported as an affordable, effective ivermectin option with good parasite control and minimal adverse effects, though some users note variability between batches or suppliers. Overall sentiment is positive for routine use."

  • Stable superstar

  • Generic ivermectin 1% injectable offering cost-effective broad-spectrum nematode control.

  • Stable superstar

  • Generic ivermectin 1% injectable offering cost-effective broad-spectrum nematode control.

Increased Safety & Security

Time-Saving Convenience

Noromectin Injection is a competitively priced doramectin formulation from a specialist veterinary manufacturer, combining the longer persistence of doramectin-class actives with accessible regional availability for equine use. Its market strength derives from cost-competitive sourcing and clear labeling for a range of livestock, making it attractive for practices seeking an affordable, longer-acting macrocyclic lactone alternative to premium brands. In comparative programs it is often chosen where doramectin’s persistence is desired but budget constraints favor generics over marketed market-leaders.

  • Moxidectin muscle

  • Persistent worm shield

  • Stable superstar

  • Generic ivermectin 1% injectable offering cost-effective broad-spectrum nematode control.

  • Often sold in larger vial sizes suitable for multiple animals or herd treatments.

  • Moxidectin muscle

  • Persistent worm shield

  • Stable superstar

  • Generic ivermectin 1% injectable offering cost-effective broad-spectrum nematode control.

  • Often sold in larger vial sizes suitable for multiple animals or herd treatments.

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$50-140 CAD

5
LONG-ACTING MOXIDECTIN OPTION

Cydectin Injectable

Cydectin Injectable

Cydectin Injectable (moxidectin) holds a leading technical reputation in equine anthelmintics for its extended activity spectrum, including improved efficacy against encysted small strongyles, which gives it a distinct clinical advantage over standard ivermectin injectables. It is frequently selected for strategic control of difficult-to-treat life stages despite typically higher per-dose cost, offering long-term program benefits that can offset upfront expense. When compared to doramectin and ivermectin options on this list, Cydectin is chosen where efficacy against encysted parasites and prolonged protection are priority considerations.

4.5
★★★★☆
  • Long residual control

  • Deep gut reach

  • Long residual control

  • Deep gut reach

Review Summary

85%

"Cydectin Injectable (moxidectin) is highly rated for its potency and ability to control resistant and encysted parasites, with many users seeing superior long-term reduction in burdens; veterinarians caution careful dosing in foals and debilitated horses. Its strong efficacy earns strong approval despite occasional safety concerns."

  • Horse-happier days

  • Contains moxidectin, noted for longer persistent activity and efficacy against some resistant nematodes.

  • Horse-happier days

  • Contains moxidectin, noted for longer persistent activity and efficacy against some resistant nematodes.

Increased Safety & Security

Time-Saving Convenience

Recreational Enjoyment

Cydectin Injectable (moxidectin) holds a leading technical reputation in equine anthelmintics for its extended activity spectrum, including improved efficacy against encysted small strongyles, which gives it a distinct clinical advantage over standard ivermectin injectables. It is frequently selected for strategic control of difficult-to-treat life stages despite typically higher per-dose cost, offering long-term program benefits that can offset upfront expense. When compared to doramectin and ivermectin options on this list, Cydectin is chosen where efficacy against encysted parasites and prolonged protection are priority considerations.

  • Long residual control

  • Deep gut reach

  • Horse-happier days

  • Contains moxidectin, noted for longer persistent activity and efficacy against some resistant nematodes.

  • Many Cydectin injectable formulations are labeled for cattle; equine products are typically moxidectin oral gels rather than injectables.

  • Long residual control

  • Deep gut reach

  • Horse-happier days

  • Contains moxidectin, noted for longer persistent activity and efficacy against some resistant nematodes.

  • Many Cydectin injectable formulations are labeled for cattle; equine products are typically moxidectin oral gels rather than injectables.

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$100-260 CAD

Research and Practical Evidence Supporting Injectable Equine Anthelmintics

Injectable anthelmintics are supported by pharmacology and field studies showing rapid systemic distribution and high efficacy against a broad spectrum of equine parasites. The main active classes represented in this list — macrocyclic lactones (including ivermectin and moxidectin) and related avermectins/doramectin‑type compounds — have extensive peer‑reviewed evidence for strong efficacy against large strongyles, bots, and many small strongyle stages. At the same time, a growing body of research highlights emerging resistance in cyathostomins to some macrocyclic lactones and underscores the value of targeted selective treatments, fecal egg count monitoring, and integrated pasture management. For practical use, veterinary studies and extension guidance emphasize correct dose calculation by bodyweight, attention to injection technique to avoid local reactions, and following regional regulations on labelled uses and withholding periods.

Macrocyclic lactones (ivermectin, moxidectin) show high efficacy against large strongyles, bots, and many encysted stages in controlled studies; moxidectin demonstrates extended activity and efficacy against some encysted cyathostomin stages.

Field reports and peer‑reviewed studies from North America and Europe document instances of reduced efficacy and early signs of resistance in cyathostomins to ivermectin-class products, making resistance management essential.

Fecal egg count monitoring and fecal egg count reduction tests (FECRT) are recommended scientific methods to evaluate product performance on individual farms and to guide targeted selective treatment decisions.

Pharmacokinetic research indicates injectable formulations provide rapid systemic exposure compared with some topical products; however, safety analyses note the importance of proper dilution, injection site selection, and strict adherence to labelled directions or veterinary prescription.

Integrated parasite control combining strategic anthelmintic use, pasture rotation, stocking density management, and targeted treatments yields better long‑term control and slows the development of resistance than reliance on frequent blanket treatments alone.

In the Canadian context these injectables — Eqvalan Injection, Dectomax Injectable, Ivomec Plus Injection, Noromectin Injection, and Cydectin Injectable — provide a range of options for strategic and high‑burden deworming programs. Eqvalan and Ivomec Plus are commonly used for broad‑spectrum coverage, Dectomax offers an alternative avermectin profile where available, Noromectin provides another choice within the same pharmacological family, and Cydectin Injectable (moxidectin) is often the best choice among these five for situations where extended activity and efficacy against encysted cyathostomins are a priority. We hope you found the product overview you were looking for — you can refine or expand your search using the site search to compare labels, withdrawal times, and veterinary guidance specific to your province.

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