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Top 5 Trace Mineral Immune Support Options in Canada for 2025: Vet-Grade Zinc & Selenium Formulas for Small Animals — Which Offers the Best Bioavailability and Safety?

Published on Thursday, August 21, 2025

Targeted trace mineral supplements supplying bioavailable zinc and selenium are increasingly popular in Canada for 2025 because they support immune cell function, antioxidant enzyme systems, and skin barrier integrity in small animals. Consumers in the Canadian pet market are choosing formulations that emphasize chelated minerals, evidence-based dosing, and absorption-enhancing pairings such as probiotics — all delivered in convenient formats like chews, powders, and liquids. Buyers prefer products with veterinary input, third-party testing, clear labeling, and sustainability credentials, while still balancing effectiveness and safety given the narrow therapeutic window for selenium and the competitive absorption dynamics of zinc.

Quick Menu

1. Best Budget Trace Mineral Support for Seniors

2. Best Chewable Multivitamin with Mineral Support

3. Best High-Potency Immune & Trace Mineral Formula

4. Best Veterinary-Grade Zinc & Selenium Support

5. Best Complementary Trace Mineral Immune Blend

1
BEST BUDGET TRACE MINERAL SUPPORT FOR SENIORS

NaturVet VitaPet Senior Daily Vitamins Plus Glucosamine

NaturVet

An affordable senior-focused multivitamin that includes basic levels of trace minerals such as zinc and selenium to support aging dogs; it earns a position here as the budget-friendly baseline for owners prioritizing cost and joint support. Compared with specialized or veterinary-grade options on this list, NaturVet offers lower concentrated trace mineral dosing but has the financial advantage of wide retail availability and a low price per serving.

4.4
★★★★☆
  • Senior-tailored boost

  • Hip-friendly glucosamine

  • Senior-tailored boost

  • Hip-friendly glucosamine

Review Summary

88%

"Most buyers find NaturVet VitaPet Senior Daily Vitamins Plus Glucosamine an easy-to-give, palatable chew that helps with mobility and coat condition in senior dogs, though some see little to no noticeable improvement and report occasional smell or texture complaints."

  • Soft-chew spa

  • Daily multivitamin tailored for senior dogs with added glucosamine for joint support.

  • Soft-chew spa

  • Daily multivitamin tailored for senior dogs with added glucosamine for joint support.

Increased Safety & Security

Time-Saving Convenience

An affordable senior-focused multivitamin that includes basic levels of trace minerals such as zinc and selenium to support aging dogs; it earns a position here as the budget-friendly baseline for owners prioritizing cost and joint support. Compared with specialized or veterinary-grade options on this list, NaturVet offers lower concentrated trace mineral dosing but has the financial advantage of wide retail availability and a low price per serving.

  • Senior-tailored boost

  • Hip-friendly glucosamine

  • Soft-chew spa

  • Daily multivitamin tailored for senior dogs with added glucosamine for joint support.

  • Provides broad-spectrum vitamins and minerals to support overall health.

  • Senior-tailored boost

  • Hip-friendly glucosamine

  • Soft-chew spa

  • Daily multivitamin tailored for senior dogs with added glucosamine for joint support.

  • Provides broad-spectrum vitamins and minerals to support overall health.

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From 33.48$
2
BEST CHEWABLE MULTIVITAMIN WITH MINERAL SUPPORT

Zesty Paws Multivitamin for Dogs 8-in-1 Bites

Zesty Paws

Palatable soft-chew multivitamins that supply supplemental zinc and selenium while maximizing owner and pet compliance, making them a top consumer choice for everyday immune support. Versus NaturVet it trades highly concentrated trace mineral dosing for taste and convenience, and compared with veterinary formulas like Thorne or NuVet it is mid-priced with strong retail and subscription distribution but lacks the same level of clinical-grade purity.

4.6
★★★★☆
  • Treat-like multiboost

  • Skin & coat glow

  • Treat-like multiboost

  • Skin & coat glow

Review Summary

93%

"Zesty Paws Multivitamin for Dogs 8-in-1 Bites is widely praised for taste and visible benefits to coat, energy, and digestion; a minority report stomach upset or think the price is high for the quantity."

  • Flavor-party crunch

  • Soft-bite chews combining multiple vitamins, minerals and antioxidants for general wellness.

  • Flavor-party crunch

  • Soft-bite chews combining multiple vitamins, minerals and antioxidants for general wellness.

Recreational Enjoyment

Increased Safety & Security

Time-Saving Convenience

Palatable soft-chew multivitamins that supply supplemental zinc and selenium while maximizing owner and pet compliance, making them a top consumer choice for everyday immune support. Versus NaturVet it trades highly concentrated trace mineral dosing for taste and convenience, and compared with veterinary formulas like Thorne or NuVet it is mid-priced with strong retail and subscription distribution but lacks the same level of clinical-grade purity.

  • Treat-like multiboost

  • Skin & coat glow

  • Flavor-party crunch

  • Soft-bite chews combining multiple vitamins, minerals and antioxidants for general wellness.

  • Formulated to support skin, coat, digestion and immune health in one chew.

  • Treat-like multiboost

  • Skin & coat glow

  • Flavor-party crunch

  • Soft-bite chews combining multiple vitamins, minerals and antioxidants for general wellness.

  • Formulated to support skin, coat, digestion and immune health in one chew.

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From 39.97$
3
BEST HIGH-POTENCY IMMUNE & TRACE MINERAL FORMULA

NuVet Plus Canine Supplement

NuVet Plus Canine Supplement

Veterinarian-formulated, concentrated canine supplement known for higher levels of immune-supporting nutrients, including bioavailable zinc and selenium, positioning it as a clinical-strength option for targeted mineral repletion. Financially it sits above mainstream chewables, but its technical advantage is a more aggressive, vet-endorsed dosing profile and ingredient focus compared with the more consumer-oriented NaturVet and Zesty Paws.

4.3
★★★★☆
  • Veterinary-grade shield

  • Immune-focused formula

  • Veterinary-grade shield

  • Immune-focused formula

Review Summary

84%

"NuVet Plus Canine Supplement has many long-term devotees who credit it with improved immune health and overall condition, but reviews are mixed with critics noting high cost, subscription issues, and limited objective evidence of effect."

  • Easy-dosing powder

  • High-potency powdered supplement aimed at comprehensive immune and nutritional support.

  • Easy-dosing powder

  • High-potency powdered supplement aimed at comprehensive immune and nutritional support.

Increased Safety & Security

Time-Saving Convenience

Veterinarian-formulated, concentrated canine supplement known for higher levels of immune-supporting nutrients, including bioavailable zinc and selenium, positioning it as a clinical-strength option for targeted mineral repletion. Financially it sits above mainstream chewables, but its technical advantage is a more aggressive, vet-endorsed dosing profile and ingredient focus compared with the more consumer-oriented NaturVet and Zesty Paws.

  • Veterinary-grade shield

  • Immune-focused formula

  • Easy-dosing powder

  • High-potency powdered supplement aimed at comprehensive immune and nutritional support.

  • Provides a broad spectrum of vitamins, antioxidants and mineral cofactors for long-term health.

  • Veterinary-grade shield

  • Immune-focused formula

  • Easy-dosing powder

  • High-potency powdered supplement aimed at comprehensive immune and nutritional support.

  • Provides a broad spectrum of vitamins, antioxidants and mineral cofactors for long-term health.

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$90-140 CAD

4
BEST VETERINARY-GRADE ZINC & SELENIUM SUPPORT

Thorne Research Veterinary ImmunoSupport Formula

Thorne Research Veterinary ImmunoSupport Formula

Market-leading veterinary formula prized for pharmaceutical-grade sourcing, precise zinc and selenium dosing, and third-party testing, making it the preferred choice when reliable, clinically validated trace mineral immune support is required. While it carries a premium price, its technical superiority in purity, manufacturing standards, and evidence-backed formulation distinguishes it from the more general multivitamins and puts it ahead for veterinary use.

4.5
★★★★☆
  • Clinician-strength support

  • Trace-mineral balance

  • Clinician-strength support

  • Trace-mineral balance

Review Summary

89%

"Thorne Research Veterinary ImmunoSupport Formula is commended for high-quality, vet-formulated ingredients and perceived immune benefits in some pets, though it is considered expensive and results can vary between animals."

  • Lab-smart purity

  • Clinically oriented veterinary formula focused on immune system support.

  • Lab-smart purity

  • Clinically oriented veterinary formula focused on immune system support.

Increased Safety & Security

Time-Saving Convenience

Market-leading veterinary formula prized for pharmaceutical-grade sourcing, precise zinc and selenium dosing, and third-party testing, making it the preferred choice when reliable, clinically validated trace mineral immune support is required. While it carries a premium price, its technical superiority in purity, manufacturing standards, and evidence-backed formulation distinguishes it from the more general multivitamins and puts it ahead for veterinary use.

  • Clinician-strength support

  • Trace-mineral balance

  • Lab-smart purity

  • Clinically oriented veterinary formula focused on immune system support.

  • Manufactured to professional standards with targeted nutrients for immune function.

  • Clinician-strength support

  • Trace-mineral balance

  • Lab-smart purity

  • Clinically oriented veterinary formula focused on immune system support.

  • Manufactured to professional standards with targeted nutrients for immune function.

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$70-120 CAD

5
BEST COMPLEMENTARY TRACE MINERAL IMMUNE BLEND

Omega Alpha E-Z Immunity

Omega Alpha E-Z Immunity

Australian-formulated immune support that combines trace minerals like zinc and selenium with antioxidants and botanical extracts, offering a complementary approach valued for formulation breadth and natural-ingredient profiling. Compared with Thorne and NuVet it emphasizes botanical synergy over purely clinical dosing, often at a comparable or slightly lower price point and with the advantage of regional manufacturing for buyers in Australia and nearby markets.

4.3
★★★★☆
  • Liquid immune boost

  • Rapid-absorb delivery

  • Liquid immune boost

  • Rapid-absorb delivery

Review Summary

86%

"Omega Alpha E-Z Immunity is appreciated by many for easy dosing and reported improvements in digestive and immune resilience, but a subset of users find it costly and notice inconsistent outcomes."

  • Syringe-friendly sip

  • Formulated as a complementary immune support blend for recovery and resilience.

  • Syringe-friendly sip

  • Formulated as a complementary immune support blend for recovery and resilience.

Increased Safety & Security

Time-Saving Convenience

Australian-formulated immune support that combines trace minerals like zinc and selenium with antioxidants and botanical extracts, offering a complementary approach valued for formulation breadth and natural-ingredient profiling. Compared with Thorne and NuVet it emphasizes botanical synergy over purely clinical dosing, often at a comparable or slightly lower price point and with the advantage of regional manufacturing for buyers in Australia and nearby markets.

  • Liquid immune boost

  • Rapid-absorb delivery

  • Syringe-friendly sip

  • Formulated as a complementary immune support blend for recovery and resilience.

  • Designed for easy dosing and compatibility with other treatments.

  • Liquid immune boost

  • Rapid-absorb delivery

  • Syringe-friendly sip

  • Formulated as a complementary immune support blend for recovery and resilience.

  • Designed for easy dosing and compatibility with other treatments.

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$45-90 CAD

Why Zinc and Selenium Matter: Science in Plain Language

Zinc and selenium play complementary roles in immune health. Zinc is central to immune cell signaling, wound repair, and maintaining a strong skin and mucosal barrier. Selenium is a key cofactor for antioxidant enzymes (for example, glutathione peroxidases) that reduce oxidative stress during immune responses. When properly formulated — using chelated mineral forms and absorption aids like probiotics — these trace minerals are more bioavailable and better tolerated. Beginner-friendly research highlights support targeted, balanced supplementation under veterinary guidance rather than ad hoc high-dose use.

Zinc supports the development and function of multiple immune cells (including T-cells and natural killer cells) and contributes to skin and coat health.

Selenium is essential for antioxidant enzymes that protect cells from oxidative damage during infection and inflammation.

Chelated forms of zinc and selenium generally show improved absorption and reduced gastric irritation compared with simple inorganic salts.

Pairing trace minerals with probiotics and certain vitamins can improve uptake and clinical outcomes in some studies, especially in animals with digestive compromise.

Clinical and preclinical veterinary studies indicate improved immune markers and recovery times with balanced trace mineral supplementation, but results depend on baseline nutritional status and formulation quality.

Because selenium and zinc can be toxic at high doses or interfere with other minerals, safe supplementation should follow product labeling and veterinary advice.

In the Canadian 2025 market, targeted trace mineral immune support products like NaturVet VitaPet Senior Daily Vitamins Plus Glucosamine, Zesty Paws Multivitamin for Dogs 8-in-1 Bites, NuVet Plus Canine Supplement, Thorne Research Veterinary ImmunoSupport Formula, and Omega Alpha E-Z Immunity offer a range of formats and ingredient philosophies for different needs. For pet owners seeking a clinician-grade, rigorously formulated option with a strong focus on bioavailability and testing, Thorne Research Veterinary ImmunoSupport Formula stands out as the best single choice among these five. We hope you found what you were looking for; use the site search to refine by life stage, dosage form, or veterinary recommendation if you want to narrow or expand your options.

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