2025 Guide: Single-Strain Probiotics for Small Animals in Canada — 5 Vet-Backed Options to Target Digestive and Immune Health (Which Fits Your Pet?)

Bene-Bac Plus Pet Gel is positioned as a practical, pocket-sized gel formulation favored for easy oral dosing in small animals, making it a go-to choice for fluid-sensitive or hard-to-medicate patients. Its technical advantage is the gel vehicle that improves palatability and dosing accuracy and often comes at a lower price point than veterinary prescription blends, though it is less narrowly targeted than single-strain yeast products like Protexin Bio‑Kult S. boulardii.

Protexin Bio‑Kult S. boulardii is the single-strain Saccharomyces boulardii offering on this list, valued for its targeted use in acute gastrointestinal upset in small animals; its single-strain focus appeals to clinicians who prefer a defined mechanism of action over multi-strain mixes. While typically positioned at a premium compared with budget gel formats, its technical simplicity and established use make it an attractive single-strain option compared with broader-spectrum products such as Nutramax Proviable‑DC.

Nutramax Proviable‑DC is the market-leading multi-strain veterinary probiotic known for its broad-spectrum strain profile and veterinarian-focused packaging, offering a comprehensive approach to gut support that contrasts with single-strain offerings on this list. Its financial and technical strengths are brand recognition and perceived clinical versatility — typically commanding higher price points but often preferred when clinicians want a multi-strain regimen rather than a single-strain yeast or simple gel.

Vetri‑Science Vetri Mega Probiotic is a veterinarian-oriented supplement that balances cost and broad maintenance support for small companion animals, marketed for routine digestive and immune health rather than acute single-strain interventions. Compared with dedicated single-strain products like Protexin Bio‑Kult S. boulardii it emphasizes ongoing wellness and palatability (soft chew or capsule formats), offering a mid-range financial option between budget gels and premium veterinary formulations.