Top 9 Prescription Diet Foods for Dogs in Canada — 2025 Veterinarian-Approved Guide to Managing Kidney Disease, Allergies, Diabetes and GI Disorders

Hill's Prescription Diet k/d Kidney Care is a long-established, prescription renal diet with a substantial clinical evidence base and wide-format availability (dry and wet), which makes it a frequent first choice for veterinarians managing chronic kidney conditions. Compared with the other options on this list, k/d is noted for palatability and proven study support but is typically positioned at a premium price point relative to value-focused alternatives.

Royal Canin Veterinary Diet Hepatic Canned provides the same hepatic‑specific nutrient control as the dry formula but in a high‑moisture, highly palatable wet format that helps maintain hydration and stimulate appetite in anorexic or finicky patients. It stands out for delivering the brand's precise formulation in a wet product—useful when comparing to Hill's canned option for clinical evidence and Purina's economical wet choices—though it is typically higher cost per feeding than dry alternatives.

Hill's z/d is a hydrolyzed-protein, hypoallergenic prescription diet designed primarily for elimination trials and food-sensitivity cases, making it uniquely suited when GI signs are suspected to be diet-related rather than purely inflammatory or infectious. Although typically more expensive than general GI diets on this list, its technical advantage in allergy testing and long-term management can reduce diagnostic costs and unnecessary therapeutic changes.

Hill's w/d canned delivers the brand's multi-benefit approach—weight, digestive, urinary and glucose management—in a wet format, combining hydration and taste appeal with broad therapeutic targets. Relative to Royal Canin's glycemic-focused canned product, Hill's emphasizes comorbidity management which can eliminate the need for multiple specialty diets, and compared with Purina DM it offers a clinician-trusted wet option supported by Hill's clinical research and distribution network.

Hill's c/d Multicare is often chosen for its broad clinical evidence and proven track record in reducing recurrence of both struvite and calcium oxalate-related urinary problems, offering comprehensive long-term urinary health support. Compared with Royal Canin SO and Purina UR, c/d is marketed with extensive clinical studies and veterinary support materials, which can justify a slightly higher price for practices prioritizing scientific backing and patient outcomes. Its financial trade-off is higher per-bag cost in exchange for a robust prevention profile and formulations that promote increased water intake and urinary comfort.

Purina Pro Plan HA delivers a hydrolyzed-protein prescription option that emphasizes palatability and value, making it a competitive choice for owners seeking an effective but cost-conscious solution for dermatology and food-sensitivity management. In comparison to Royal Canin and Hill's products it often undercuts on price and benefits from wide distribution, though it may be considered slightly less specialized than ultra-hydrolyzed or elemental diets like Ultamino for the most severe cases.

Royal Canin Veterinary Diet Gastrointestinal Low Fat is positioned as a clinic-favorite for pancreatitis because its formula is specifically balanced for ultra-low fat and precise nutrient profiles developed from extensive veterinary research. Compared with the other options on this list, Royal Canin’s scale and formulation consistency deliver predictable clinical results and purchasing efficiencies for veterinary practices, often making it a cost-effective staple in hospital formularies.

Hill's h/d Heart Care is a long-standing prescription diet formulated to support dogs with heart disease through sodium restriction, targeted taurine and L‑carnitine supplementation, and omega‑3 fatty acids to support cardiac function. It holds a market leader position because of extensive clinical use, high palatability and broad veterinary distribution, which often makes it financially accessible through clinics compared with smaller specialty brands; compared with Royal Canin and Purina it is distinguished by its long clinical track record and clinic-level availability.