Simparica Trio Auto-Ship
Simparica Trio's auto-ship service is positioned as best-in-class for owners who want a single, monthly oral chew that combines flea, tick, heartworm and intestinal parasite protection into one prescription — reducing the need to buy multiple products. Its technical advantage is the all-in-one formulation and palatable chewability that improve compliance compared with topical monthly preventives, and its subscription pricing often delivers better per-dose value over buying separate agents like a monthly heartworm pill plus a flea product.
Triple-action shield
Auto-ship peace
Triple-action shield
Auto-ship peace
Review Summary
"Users report excellent combined flea, tick and heartworm protection and praise the convenience of auto-ship; a minority note GI upset or lethargy after doses. Overall customers value the single monthly chewable and timely refills."
Chicken-treat cheers
Monthly chew combining flea, tick, heartworm and common intestinal parasite protection in one prescription product.
Chicken-treat cheers
Monthly chew combining flea, tick, heartworm and common intestinal parasite protection in one prescription product.
Increased Safety & Security
Time-Saving Convenience
Simparica Trio's auto-ship service is positioned as best-in-class for owners who want a single, monthly oral chew that combines flea, tick, heartworm and intestinal parasite protection into one prescription — reducing the need to buy multiple products. Its technical advantage is the all-in-one formulation and palatable chewability that improve compliance compared with topical monthly preventives, and its subscription pricing often delivers better per-dose value over buying separate agents like a monthly heartworm pill plus a flea product.
Triple-action shield
Auto-ship peace
Chicken-treat cheers
Monthly chew combining flea, tick, heartworm and common intestinal parasite protection in one prescription product.
Designed for convenient auto-ship subscription with weight-based dosing and reminders.
Triple-action shield
Auto-ship peace
Chicken-treat cheers
Monthly chew combining flea, tick, heartworm and common intestinal parasite protection in one prescription product.
Designed for convenient auto-ship subscription with weight-based dosing and reminders.
$360-720 CAD
NexGard Spectra Subscription
NexGard Spectra's subscription offering shines as a market leader for chewable, monthly broad-spectrum protection, with widespread veterinary use and a reputation for palatability and steady efficacy against fleas, ticks and intestinal worms. Financially it can be competitive with other monthly chews and subscriptions commonly include vet oversight and discounts, making it a close alternative to Simparica Trio for owners prioritizing oral dosing and frequent, predictable refills.
Broad-spectrum guard
Subscription simple
Broad-spectrum guard
Subscription simple
Review Summary
"Owners praise the broad parasite coverage and easy monthly chewable format, with auto-delivery reducing missed doses; occasional vomiting or lethargy is reported by a small number of users. Many reviewers cite consistent effectiveness against fleas and worms."
Beef-flavored boost
Monthly beef-flavored chew that protects against fleas, ticks, heartworm and several intestinal worms.
Beef-flavored boost
Monthly beef-flavored chew that protects against fleas, ticks, heartworm and several intestinal worms.
Increased Safety & Security
Time-Saving Convenience
NexGard Spectra's subscription offering shines as a market leader for chewable, monthly broad-spectrum protection, with widespread veterinary use and a reputation for palatability and steady efficacy against fleas, ticks and intestinal worms. Financially it can be competitive with other monthly chews and subscriptions commonly include vet oversight and discounts, making it a close alternative to Simparica Trio for owners prioritizing oral dosing and frequent, predictable refills.
Broad-spectrum guard
Subscription simple
Beef-flavored boost
Monthly beef-flavored chew that protects against fleas, ticks, heartworm and several intestinal worms.
Widely available as a subscription with scheduled refills and dose adjustments by weight.
Broad-spectrum guard
Subscription simple
Beef-flavored boost
Monthly beef-flavored chew that protects against fleas, ticks, heartworm and several intestinal worms.
Widely available as a subscription with scheduled refills and dose adjustments by weight.
$300-660 CAD
Bravecto Plus Auto-Delivery
Bravecto Plus stands out for owners who prefer low-frequency dosing: its extended-duration formulation (doses that cover multiple months) reduces shipping and admin events, delivering clear convenience and potential annual cost savings versus monthly plans. Technically, the multi-month protection lowers the risk of missed doses inherent to monthly programs like Revolution Plus or Advantage Multi, making its auto-delivery model attractive for busy households despite fewer refill touchpoints with the clinic.
12-week freedom
Auto-delivery calm
12-week freedom
Auto-delivery calm
Review Summary
"Many users appreciate longer-acting flea and tick control and fewer dosing events with auto-delivery, though some report adverse reactions or variable efficacy on certain ticks. Reviewers frequently mention convenience but note a higher price point for extended protection."
Chewable thrill
Long-interval formulation that reduces dosing frequency (fewer doses per year than monthly options) for fleas and ticks.
Chewable thrill
Long-interval formulation that reduces dosing frequency (fewer doses per year than monthly options) for fleas and ticks.
Increased Safety & Security
Time-Saving Convenience
Bravecto Plus stands out for owners who prefer low-frequency dosing: its extended-duration formulation (doses that cover multiple months) reduces shipping and admin events, delivering clear convenience and potential annual cost savings versus monthly plans. Technically, the multi-month protection lowers the risk of missed doses inherent to monthly programs like Revolution Plus or Advantage Multi, making its auto-delivery model attractive for busy households despite fewer refill touchpoints with the clinic.
12-week freedom
Auto-delivery calm
Chewable thrill
Long-interval formulation that reduces dosing frequency (fewer doses per year than monthly options) for fleas and ticks.
Available on auto-delivery so households get the next dose timed to extended protection intervals.
12-week freedom
Auto-delivery calm
Chewable thrill
Long-interval formulation that reduces dosing frequency (fewer doses per year than monthly options) for fleas and ticks.
Available on auto-delivery so households get the next dose timed to extended protection intervals.
$300-520 CAD
Revolution Plus Monthly Refill
Revolution Plus's monthly refill program is a top choice for owners seeking a topical, prescription-strength preventive with broad parasite coverage and the familiarity of a monthly schedule that pairs well with routine vet visits. Compared with oral chews, its topical route can be preferable for dogs that don’t reliably take pills, and subscription plans typically include reminders and steady pricing that help keep annual prevention costs predictable against competitors like Simparica Trio or NexGard Spectra.
Monthly guardian
Refill-on-repeat
Monthly guardian
Refill-on-repeat
Review Summary
"Reviewers like the broad topical protection (fleas, ticks, mites, some worms) and the steady monthly refill schedule that helps maintain adherence; a subset report local skin irritation or inconsistent absorption. Overall feedback emphasizes effectiveness with occasional tolerability issues."
Waterproof wink
Monthly topical that covers fleas, ticks, heartworm prevention and common intestinal parasites under prescription.
Waterproof wink
Monthly topical that covers fleas, ticks, heartworm prevention and common intestinal parasites under prescription.
Increased Safety & Security
Revolution Plus's monthly refill program is a top choice for owners seeking a topical, prescription-strength preventive with broad parasite coverage and the familiarity of a monthly schedule that pairs well with routine vet visits. Compared with oral chews, its topical route can be preferable for dogs that don’t reliably take pills, and subscription plans typically include reminders and steady pricing that help keep annual prevention costs predictable against competitors like Simparica Trio or NexGard Spectra.
Monthly guardian
Refill-on-repeat
Waterproof wink
Monthly topical that covers fleas, ticks, heartworm prevention and common intestinal parasites under prescription.
Subscription refills and automatic renewals simplify monthly dosing and ensure uninterrupted protection.
Monthly guardian
Refill-on-repeat
Waterproof wink
Monthly topical that covers fleas, ticks, heartworm prevention and common intestinal parasites under prescription.
Subscription refills and automatic renewals simplify monthly dosing and ensure uninterrupted protection.
$420-720 CAD
Advantage Multi Auto-Renewal
Advantage Multi remains a strong market option for monthly, topical heartworm and ectoparasite prevention backed by a long clinical track record and broad veterinary acceptance, with auto-renewal smoothing supply and adherence for owners. Its technical advantage is a well-established formulation that many clinics bundle into wellness plans, often producing competitive per-month pricing versus newer combination chews and making it a pragmatic choice for steady, clinic-managed subscription care.
Multi-parasite shield
Auto-renew ease
Multi-parasite shield
Auto-renew ease
Review Summary
"Longstanding, trusted topical that many owners find reliable for parasite control, and auto-renewal is appreciated for keeping doses current; criticisms focus on application mess, odor, or occasional side effects. Many reviewers remain loyal but note handling drawbacks."
Vet-favorite flavor
Monthly topical combining flea control with heartworm prevention and intestinal parasite coverage at a competitive price.
Vet-favorite flavor
Monthly topical combining flea control with heartworm prevention and intestinal parasite coverage at a competitive price.
Increased Safety & Security
Time-Saving Convenience
Advantage Multi remains a strong market option for monthly, topical heartworm and ectoparasite prevention backed by a long clinical track record and broad veterinary acceptance, with auto-renewal smoothing supply and adherence for owners. Its technical advantage is a well-established formulation that many clinics bundle into wellness plans, often producing competitive per-month pricing versus newer combination chews and making it a pragmatic choice for steady, clinic-managed subscription care.
Multi-parasite shield
Auto-renew ease
Vet-favorite flavor
Monthly topical combining flea control with heartworm prevention and intestinal parasite coverage at a competitive price.
Auto-renewal subscription helps maintain consistent monthly protection and supplies.
Multi-parasite shield
Auto-renew ease
Vet-favorite flavor
Monthly topical combining flea control with heartworm prevention and intestinal parasite coverage at a competitive price.
Auto-renewal subscription helps maintain consistent monthly protection and supplies.
$300-540 CAD