K9 Advantix II Auto-Ship
K9 Advantix II Auto-Ship leverages an established brand reputation and monthly auto-ship convenience to keep dogs continuously protected against fleas, ticks and mosquitoes; its topical repellency profile gives it a technical edge for owners worried about biting insects. Compared with longer-interval products in this list, K9 Advantix II’s monthly cadence can mean higher shipment frequency but often lower per-dose cost than extended-action options like Bravecto, and broader repellency than flea-only alternatives such as Advantage II.
Repels mosquitoes
Swim-ready protection
Repels mosquitoes
Swim-ready protection
Review Summary
"Buyers commonly praise K9 Advantix II for rapid flea and tick knockdown and mosquito repellency, and many subscribe for the convenience; however, some report mild skin irritation in sensitive dogs and a strong warning about fatal toxicity if applied to cats. Overall users find it effective but caution about species safety and occasional local reactions."
No-tick selfies
Monthly topical (imidacloprid + permethrin) that repels and kills fleas, ticks and mosquitoes.
No-tick selfies
Monthly topical (imidacloprid + permethrin) that repels and kills fleas, ticks and mosquitoes.
Increased Safety & Security
Time-Saving Convenience
Recreational Enjoyment
K9 Advantix II Auto-Ship leverages an established brand reputation and monthly auto-ship convenience to keep dogs continuously protected against fleas, ticks and mosquitoes; its topical repellency profile gives it a technical edge for owners worried about biting insects. Compared with longer-interval products in this list, K9 Advantix II’s monthly cadence can mean higher shipment frequency but often lower per-dose cost than extended-action options like Bravecto, and broader repellency than flea-only alternatives such as Advantage II.
Repels mosquitoes
Swim-ready protection
No-tick selfies
Monthly topical (imidacloprid + permethrin) that repels and kills fleas, ticks and mosquitoes.
Weight-based dosing to cover a wide range of dog sizes; not safe for use on cats.
Repels mosquitoes
Swim-ready protection
No-tick selfies
Monthly topical (imidacloprid + permethrin) that repels and kills fleas, ticks and mosquitoes.
Weight-based dosing to cover a wide range of dog sizes; not safe for use on cats.
Revolution Plus Subscribe & Save
Revolution Plus Subscribe & Save stands out as the broadest-spectrum monthly topical subscription, combining flea, tick and internal parasite protection with heartworm prevention in one shipment, which economically replaces multiple separate products for many households. Its financial advantage comes from reducing the need for additional prescriptions and consolidating coverage under a single auto-refill plan, making it a preferable choice for owners seeking comprehensive protection versus the primarily ectoparasite-focused spot-ons on this list.
Monthly full-coverage
Heartworm defense
Monthly full-coverage
Heartworm defense
Review Summary
"Revolution Plus gets strong reviews for broad-spectrum protection (fleas, ticks, heartworm, mites and some intestinal parasites) and the subscription convenience, with users noting excellent efficacy and low side effects in most pets. A minority report mild digestive or skin reactions, but satisfaction and perceived value are high."
Tiny-mite ninja
Monthly topical combining selamectin + sarolaner to treat/control fleas, ticks, mites and also help prevent heartworm disease.
Tiny-mite ninja
Monthly topical combining selamectin + sarolaner to treat/control fleas, ticks, mites and also help prevent heartworm disease.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus Subscribe & Save stands out as the broadest-spectrum monthly topical subscription, combining flea, tick and internal parasite protection with heartworm prevention in one shipment, which economically replaces multiple separate products for many households. Its financial advantage comes from reducing the need for additional prescriptions and consolidating coverage under a single auto-refill plan, making it a preferable choice for owners seeking comprehensive protection versus the primarily ectoparasite-focused spot-ons on this list.
Monthly full-coverage
Heartworm defense
Tiny-mite ninja
Monthly topical combining selamectin + sarolaner to treat/control fleas, ticks, mites and also help prevent heartworm disease.
Veterinarian-prescribed product in many Canadian channels and commonly available via Subscribe & Save programs.
Monthly full-coverage
Heartworm defense
Tiny-mite ninja
Monthly topical combining selamectin + sarolaner to treat/control fleas, ticks, mites and also help prevent heartworm disease.
Veterinarian-prescribed product in many Canadian channels and commonly available via Subscribe & Save programs.
$360-600 CAD
Bravecto Topical Auto-Delivery
Bravecto Topical Auto-Delivery differentiates itself with a long-acting 12-week dosing interval, cutting the number of shipments and clinic visits required each year and improving adherence through less frequent dosing. While per-dose cost is higher than monthly products, the auto-delivery model often yields lower logistical costs and greater convenience compared with monthly subscriptions like K9 Advantix II or Advantage II, making it financially attractive for owners prioritizing fewer deliveries and sustained protection.
12-week protection
Rapid flea kill
12-week protection
Rapid flea kill
Review Summary
"Bravecto Topical is highly rated for its 3-month dosing convenience and long-lasting tick and flea control; many long-term users appreciate fewer applications and consistent protection. Some owners report occasional adverse reactions (vomiting, lethargy, localized irritation), but most say risk is low relative to the benefit."
Quarterly chill
Topical fluralaner formulation that provides up to 12 weeks of flea and tick protection per dose.
Quarterly chill
Topical fluralaner formulation that provides up to 12 weeks of flea and tick protection per dose.
Increased Safety & Security
Time-Saving Convenience
Recreational Enjoyment
Bravecto Topical Auto-Delivery differentiates itself with a long-acting 12-week dosing interval, cutting the number of shipments and clinic visits required each year and improving adherence through less frequent dosing. While per-dose cost is higher than monthly products, the auto-delivery model often yields lower logistical costs and greater convenience compared with monthly subscriptions like K9 Advantix II or Advantage II, making it financially attractive for owners prioritizing fewer deliveries and sustained protection.
12-week protection
Rapid flea kill
Quarterly chill
Topical fluralaner formulation that provides up to 12 weeks of flea and tick protection per dose.
Reduces dosing frequency compared with monthly products—one application every 3 months for continuous coverage.
12-week protection
Rapid flea kill
Quarterly chill
Topical fluralaner formulation that provides up to 12 weeks of flea and tick protection per dose.
Reduces dosing frequency compared with monthly products—one application every 3 months for continuous coverage.
$160-400 CAD
Advantage II Subscription Service
Advantage II Subscription Service offers a focused, cost-effective monthly topical for flea prevention with a subscription model designed to ensure uninterrupted coverage at a lower price point for flea-only needs. It is technically narrower in scope than multi-target products such as Revolution Plus, but its financial appeal lies in a simpler, typically cheaper monthly spend that can outperform broader-spectrum options for households where tick or heartworm protection is managed separately.
Fast flea kill
Stops flea eggs
Fast flea kill
Stops flea eggs
Review Summary
"Advantage II subscription users commonly report fast flea kill and fewer flea-related symptoms in dogs, praising monthly ease and value; however it does not reliably cover ticks, which disappoints buyers in tick-prone areas. Generally seen as a dependable monthly flea treatment but limited in broader parasite protection."
Itchy-free tango
Monthly topical (imidacloprid + pyriproxyfen) that kills adult fleas and prevents development of eggs and larvae.
Itchy-free tango
Monthly topical (imidacloprid + pyriproxyfen) that kills adult fleas and prevents development of eggs and larvae.
Increased Safety & Security
Time-Saving Convenience
Advantage II Subscription Service offers a focused, cost-effective monthly topical for flea prevention with a subscription model designed to ensure uninterrupted coverage at a lower price point for flea-only needs. It is technically narrower in scope than multi-target products such as Revolution Plus, but its financial appeal lies in a simpler, typically cheaper monthly spend that can outperform broader-spectrum options for households where tick or heartworm protection is managed separately.
Fast flea kill
Stops flea eggs
Itchy-free tango
Monthly topical (imidacloprid + pyriproxyfen) that kills adult fleas and prevents development of eggs and larvae.
Widely used as a cost-effective option for dogs primarily needing flea control rather than tick or heartworm coverage.
Fast flea kill
Stops flea eggs
Itchy-free tango
Monthly topical (imidacloprid + pyriproxyfen) that kills adult fleas and prevents development of eggs and larvae.
Widely used as a cost-effective option for dogs primarily needing flea control rather than tick or heartworm coverage.
$150-300 CAD
Frontline Plus Auto-Refill
Frontline Plus Auto-Refill is a widely available, veteran topical option combining fipronil and an insect growth regulator to control fleas and ticks, with auto-refill plans that prioritize continuity and retail accessibility. Positioned between flea-specific and broad-spectrum products, Frontline Plus often offers steady pricing and retail footprint advantages versus newer entrants, making it a practical subscription choice for owners seeking reliable ectoparasite control without the higher per-dose cost of long-acting alternatives.
Kills fleas & ticks
Waterproof formula
Kills fleas & ticks
Waterproof formula
Review Summary
"Frontline Plus remains a market leader for routine flea and tick control with many users noting steady performance and a long track record; some reviewers say it’s less effective against ticks compared with newer compounds and report occasional treatment failures. Overall user satisfaction is solid but mixed when compared to newer products."
Tick ninja cloak
Monthly topical (fipronil + (S)-methoprene) that kills adult fleas, ticks and targets immature flea stages.
Tick ninja cloak
Monthly topical (fipronil + (S)-methoprene) that kills adult fleas, ticks and targets immature flea stages.
Increased Safety & Security
Time-Saving Convenience
Recreational Enjoyment
Frontline Plus Auto-Refill is a widely available, veteran topical option combining fipronil and an insect growth regulator to control fleas and ticks, with auto-refill plans that prioritize continuity and retail accessibility. Positioned between flea-specific and broad-spectrum products, Frontline Plus often offers steady pricing and retail footprint advantages versus newer entrants, making it a practical subscription choice for owners seeking reliable ectoparasite control without the higher per-dose cost of long-acting alternatives.
Kills fleas & ticks
Waterproof formula
Tick ninja cloak
Monthly topical (fipronil + (S)-methoprene) that kills adult fleas, ticks and targets immature flea stages.
Long-standing market leader with broad availability and clinician familiarity, commonly used in Canadian clinics.
Kills fleas & ticks
Waterproof formula
Tick ninja cloak
Monthly topical (fipronil + (S)-methoprene) that kills adult fleas, ticks and targets immature flea stages.
Long-standing market leader with broad availability and clinician familiarity, commonly used in Canadian clinics.
$180-360 CAD