Heartgard Plus Chewables has long been a market staple for oral heartworm prevention, combining ivermectin with pyrantel to protect against heartworm, roundworms and hookworms. Its position rests on decades of clinical use and a typically lower per-dose cost compared with newer combination chewables, making it a budget-friendly baseline option versus broader-spectrum products like Simparica Trio and NexGard Spectra that also address fleas and ticks.
Heart-focused protection
Dog-approved taste
Heart-focused protection
Dog-approved taste
Review Summary
"A long-trusted monthly chewable praised for easy dosing and reliable heartworm prevention; most owners report good palatability with only rare side effects."
Monthly simplicity
Monthly chewable with ivermectin + pyrantel to prevent heartworm disease and treat common intestinal roundworms.
Monthly simplicity
Monthly chewable with ivermectin + pyrantel to prevent heartworm disease and treat common intestinal roundworms.
Increased Safety & Security
Time-Saving Convenience
Heartgard Plus Chewables has long been a market staple for oral heartworm prevention, combining ivermectin with pyrantel to protect against heartworm, roundworms and hookworms. Its position rests on decades of clinical use and a typically lower per-dose cost compared with newer combination chewables, making it a budget-friendly baseline option versus broader-spectrum products like Simparica Trio and NexGard Spectra that also address fleas and ticks.
Heart-focused protection
Dog-approved taste
Monthly simplicity
Monthly chewable with ivermectin + pyrantel to prevent heartworm disease and treat common intestinal roundworms.
Beef-flavored, easy-to-administer tablet many dogs accept readily.
Heart-focused protection
Dog-approved taste
Monthly simplicity
Monthly chewable with ivermectin + pyrantel to prevent heartworm disease and treat common intestinal roundworms.
Beef-flavored, easy-to-administer tablet many dogs accept readily.
$150-240 CAD
Panacur (fenbendazole) granules offer flexible, weight-adjustable dosing and are especially valued for treating certain protozoal infections (e.g., Giardia) and common nematodes with a well-established safety profile. Financially it is often more economical per treatment for multi-day courses than single-dose praziquantel combinations, but requires longer administration compared with one-off tablets like Drontal or Milbemax.
Food-mix friendly
Giardia-targeter
Food-mix friendly
Giardia-targeter
Review Summary
"Highly regarded for safety and effectiveness (including Giardia) with multi-day fenbendazole treatment, though the granule taste and longer dosing schedule frustrate some owners."
Flexible dosing
Fenbendazole 22.2% granules effective against roundworms, hookworms, whipworms and Giardia.
Flexible dosing
Fenbendazole 22.2% granules effective against roundworms, hookworms, whipworms and Giardia.
Increased Safety & Security
Panacur (fenbendazole) granules offer flexible, weight-adjustable dosing and are especially valued for treating certain protozoal infections (e.g., Giardia) and common nematodes with a well-established safety profile. Financially it is often more economical per treatment for multi-day courses than single-dose praziquantel combinations, but requires longer administration compared with one-off tablets like Drontal or Milbemax.
Food-mix friendly
Giardia-targeter
Flexible dosing
Fenbendazole 22.2% granules effective against roundworms, hookworms, whipworms and Giardia.
Granule format mixes with food for multi-day treatment regimens.
Food-mix friendly
Giardia-targeter
Flexible dosing
Fenbendazole 22.2% granules effective against roundworms, hookworms, whipworms and Giardia.
Granule format mixes with food for multi-day treatment regimens.
Advantage II is recognized for targeted, reliable flea control using a combination that kills adult fleas and stops immature stages, making it cost-effective for households primarily battling fleas. Relative to the other treatments here it is usually more affordable than premium multi-parasite products and avoids permethrin-related concerns, but it offers limited tick protection compared with K9 Advantix II or the broader-spectrum Revolution Plus.
Lifecycle knockout
Monthly simple
Lifecycle knockout
Monthly simple
Review Summary
"Customers praise its strong flea-killing performance and suitability for puppies, though many note it doesn't control ticks well and reapplication is often needed in heavy infestations."
Fur-friendly charm
Formulated with imidacloprid plus pyriproxyfen to rapidly kill adult fleas and inhibit eggs and larvae.
Fur-friendly charm
Formulated with imidacloprid plus pyriproxyfen to rapidly kill adult fleas and inhibit eggs and larvae.
Increased Safety & Security
Time-Saving Convenience
Advantage II is recognized for targeted, reliable flea control using a combination that kills adult fleas and stops immature stages, making it cost-effective for households primarily battling fleas. Relative to the other treatments here it is usually more affordable than premium multi-parasite products and avoids permethrin-related concerns, but it offers limited tick protection compared with K9 Advantix II or the broader-spectrum Revolution Plus.
Lifecycle knockout
Monthly simple
Fur-friendly charm
Formulated with imidacloprid plus pyriproxyfen to rapidly kill adult fleas and inhibit eggs and larvae.
Monthly topical treatment well-regarded for fast flea control and breaking infestations.
Lifecycle knockout
Monthly simple
Fur-friendly charm
Formulated with imidacloprid plus pyriproxyfen to rapidly kill adult fleas and inhibit eggs and larvae.
Monthly topical treatment well-regarded for fast flea control and breaking infestations.
NexGard is a widely available, monthly afoxolaner chewable focused specifically on flea and tick control, valued for its straightforward, single‑purpose approach and strong brand recognition. Compared with broader monthly combinations (Spectra, Simparica Trio, Credelio Plus) it is often less expensive per dose but may require purchasing additional products for heartworm or intestinal parasite protection.
Monthly flea & tick
Fast flea kill
Monthly flea & tick
Fast flea kill
Review Summary
"NexGard receives consistently positive reviews for reliably killing fleas and ticks with easy-to-administer monthly chewables; most owners report quick effectiveness and good palatability, while a minority note transient vomiting or lethargy. It is frequently recommended for routine seasonal protection."
Savory liver bite
Monthly afoxolaner chewable that reliably kills fleas and a wide range of ticks with rapid onset of action.
Savory liver bite
Monthly afoxolaner chewable that reliably kills fleas and a wide range of ticks with rapid onset of action.
Increased Safety & Security
Time-Saving Convenience
NexGard is a widely available, monthly afoxolaner chewable focused specifically on flea and tick control, valued for its straightforward, single‑purpose approach and strong brand recognition. Compared with broader monthly combinations (Spectra, Simparica Trio, Credelio Plus) it is often less expensive per dose but may require purchasing additional products for heartworm or intestinal parasite protection.
Monthly flea & tick
Fast flea kill
Savory liver bite
Monthly afoxolaner chewable that reliably kills fleas and a wide range of ticks with rapid onset of action.
Well-established product with simple once-a-month dosing and palatable formulation.
Monthly flea & tick
Fast flea kill
Savory liver bite
Monthly afoxolaner chewable that reliably kills fleas and a wide range of ticks with rapid onset of action.
Well-established product with simple once-a-month dosing and palatable formulation.
$120-220 CAD
Seresto is widely regarded as the best-in-class collar for dog flea and tick control because of its long-duration, low-maintenance design that spreads active ingredients gradually over several months, making it cost-effective over time compared with frequently replaced alternatives. It commands a premium price but delivers sustained protection and convenience that many cheaper collars on this list, like Hartz or Zodiac, do not match in terms of documented longevity and user convenience.
8-month protection — nap-ready
Water-resistant — puddle-proof
8-month protection — nap-ready
Water-resistant — puddle-proof
Review Summary
"Users report excellent, long-lasting protection (up to 8 months) and convenient, low-maintenance use; a minority of pet owners note skin irritation or other adverse events and caution from regulators. Overall praised for reliability and duration."
Low-odor comfort — nose-approved
Provides continuous, low-dose protection and repellency for up to 8 months.
Low-odor comfort — nose-approved
Provides continuous, low-dose protection and repellency for up to 8 months.
Increased Safety & Security
Time-Saving Convenience
Seresto is widely regarded as the best-in-class collar for dog flea and tick control because of its long-duration, low-maintenance design that spreads active ingredients gradually over several months, making it cost-effective over time compared with frequently replaced alternatives. It commands a premium price but delivers sustained protection and convenience that many cheaper collars on this list, like Hartz or Zodiac, do not match in terms of documented longevity and user convenience.
8-month protection — nap-ready
Water-resistant — puddle-proof
Low-odor comfort — nose-approved
Provides continuous, low-dose protection and repellency for up to 8 months.
Dual active ingredients kill and repel fleas and ticks while reducing re-infestation.
8-month protection — nap-ready
Water-resistant — puddle-proof
Low-odor comfort — nose-approved
Provides continuous, low-dose protection and repellency for up to 8 months.
Dual active ingredients kill and repel fleas and ticks while reducing re-infestation.
$55-80 CAD
Sentinel Spectrum pairs milbemycin oxime, lufenuron and praziquantel in a monthly chew that delivers heartworm prevention, comprehensive intestinal parasite control including tapeworms, and prevention of flea egg development, making it especially valuable when tapeworm or intestinal parasite coverage is a priority. Technically it does not kill adult fleas or ticks, so it is often used alongside an adulticide (or chosen where tick pressure is low), and financially it can be a cost-effective backbone product for clinics seeking strong internal parasite and tapeworm protection.
Flea-egg blocker
Pan-parasite tablet
Flea-egg blocker
Pan-parasite tablet
Review Summary
"Sentinel Spectrum is valued for preventing heartworm and a wide range of intestinal parasites (including tapeworms) and for supporting flea control via lufenuron, though it does not kill adult fleas quickly on its own. Users report reliable parasite prevention but note slower flea control compared with oral adulticides and occasional mild GI side effects."
Household-friendly guard
Combines milbemycin oxime, lufenuron and praziquantel to prevent heartworm, inhibit flea egg development and treat tapeworms.
Household-friendly guard
Combines milbemycin oxime, lufenuron and praziquantel to prevent heartworm, inhibit flea egg development and treat tapeworms.
Increased Safety & Security
Time-Saving Convenience
Sentinel Spectrum pairs milbemycin oxime, lufenuron and praziquantel in a monthly chew that delivers heartworm prevention, comprehensive intestinal parasite control including tapeworms, and prevention of flea egg development, making it especially valuable when tapeworm or intestinal parasite coverage is a priority. Technically it does not kill adult fleas or ticks, so it is often used alongside an adulticide (or chosen where tick pressure is low), and financially it can be a cost-effective backbone product for clinics seeking strong internal parasite and tapeworm protection.
Flea-egg blocker
Pan-parasite tablet
Household-friendly guard
Combines milbemycin oxime, lufenuron and praziquantel to prevent heartworm, inhibit flea egg development and treat tapeworms.
Monthly chewable provides broad intestinal parasite coverage including tapeworms not always covered by others.
Flea-egg blocker
Pan-parasite tablet
Household-friendly guard
Combines milbemycin oxime, lufenuron and praziquantel to prevent heartworm, inhibit flea egg development and treat tapeworms.
Monthly chewable provides broad intestinal parasite coverage including tapeworms not always covered by others.
$170-240 CAD
Dupray Neat Steam Cleaner
The Dupray Neat Steam Cleaner offers chemical-free high-temperature steam that kills fleas and eggs on contact, making it an ideal adjunct to vacuuming for treating mattresses, bedding, and hard surfaces where pesticides are undesirable. Economically it reduces ongoing chemical purchases and is technically complementary to the other products: use steam to sanitize and vacuums like Bissell, Dyson, or Shark to extract dead pests and debris afterward for the most effective flea-removal protocol.
Chemical-free steam
High-heat sanitizing
Chemical-free steam
High-heat sanitizing
Review Summary
"Users find it effective for chemical-free deep cleaning and sanitizing of floors and upholstery and helpful against flea eggs when used properly; common negatives are small tank capacity and longer heat-up times."
Flea-cooking magician
High-temperature steam sanitizes surfaces and can kill fleas and eggs without chemical pesticides.
Flea-cooking magician
High-temperature steam sanitizes surfaces and can kill fleas and eggs without chemical pesticides.
Increased Safety & Security
Time-Saving Convenience
The Dupray Neat Steam Cleaner offers chemical-free high-temperature steam that kills fleas and eggs on contact, making it an ideal adjunct to vacuuming for treating mattresses, bedding, and hard surfaces where pesticides are undesirable. Economically it reduces ongoing chemical purchases and is technically complementary to the other products: use steam to sanitize and vacuums like Bissell, Dyson, or Shark to extract dead pests and debris afterward for the most effective flea-removal protocol.
Chemical-free steam
High-heat sanitizing
Flea-cooking magician
High-temperature steam sanitizes surfaces and can kill fleas and eggs without chemical pesticides.
Multiple nozzles and brushes reach mattresses, upholstery, cracks and crevices where fleas and eggs hide.
Chemical-free steam
High-heat sanitizing
Flea-cooking magician
High-temperature steam sanitizes surfaces and can kill fleas and eggs without chemical pesticides.
Multiple nozzles and brushes reach mattresses, upholstery, cracks and crevices where fleas and eggs hide.
$200-350 CAD