Vetera EWT+WNV
Vetera EWT+WNV is positioned as a cost-efficient, multivalent option for equine encephalomyelitis vaccination, combining Eastern/Western/Tetanic coverage with West Nile protection to reduce the number of clinic visits. It stands out against single-focus or higher-priced multivalents on this list by offering broad coverage in a single dose, which translates to lower per-horse administration cost and streamlined herd vaccination logistics compared with some premium competitors.
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
Review Summary
"Users report strong, reliable protection from EWT and West Nile with generally mild, short-lived injection-site reactions; many horse owners and vets consider it a dependable annual combo vaccine."
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Enhanced Physical Well-Being
Time-Saving Convenience
Recreational Enjoyment
Vetera EWT+WNV is positioned as a cost-efficient, multivalent option for equine encephalomyelitis vaccination, combining Eastern/Western/Tetanic coverage with West Nile protection to reduce the number of clinic visits. It stands out against single-focus or higher-priced multivalents on this list by offering broad coverage in a single dose, which translates to lower per-horse administration cost and streamlined herd vaccination logistics compared with some premium competitors.
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Inactivated (killed) vaccine typically given as a two-dose primary series with annual boosters thereafter.
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Inactivated (killed) vaccine typically given as a two-dose primary series with annual boosters thereafter.
$35-70 CAD per dose
Prestige 5 + WNV
Prestige 5 + WNV is marketed as a premium, broad-spectrum vaccine that emphasizes extended immune response and regulatory approvals in multiple markets, making it appealing for high-value performance and show horses. Compared with more budget-focused combinations, it typically carries a higher price but offers perceived technical advantages in durability of protection and manufacturer support, making it a market-leading choice where long intervals between boosters and documented label claims are prioritized.
Five-way + WNV — broad shield
Time-saving mix — calendar-friendly
Five-way + WNV — broad shield
Time-saving mix — calendar-friendly
Review Summary
"Reviewers praise the broad coverage of Prestige 5 + WNV and its consistent immune response, though a minority note occasional transient soreness or low-grade fevers after vaccination."
Stable-ready formula — travel-tested
Multivalent product that includes protection against major encephalomyelitis strains plus West Nile virus.
Stable-ready formula — travel-tested
Multivalent product that includes protection against major encephalomyelitis strains plus West Nile virus.
Enhanced Physical Well-Being
Time-Saving Convenience
Recreational Enjoyment
Prestige 5 + WNV is marketed as a premium, broad-spectrum vaccine that emphasizes extended immune response and regulatory approvals in multiple markets, making it appealing for high-value performance and show horses. Compared with more budget-focused combinations, it typically carries a higher price but offers perceived technical advantages in durability of protection and manufacturer support, making it a market-leading choice where long intervals between boosters and documented label claims are prioritized.
Five-way + WNV — broad shield
Time-saving mix — calendar-friendly
Stable-ready formula — travel-tested
Multivalent product that includes protection against major encephalomyelitis strains plus West Nile virus.
Commonly used in routine vaccination programs with an initial series followed by yearly revaccination.
Five-way + WNV — broad shield
Time-saving mix — calendar-friendly
Stable-ready formula — travel-tested
Multivalent product that includes protection against major encephalomyelitis strains plus West Nile virus.
Commonly used in routine vaccination programs with an initial series followed by yearly revaccination.
$45-85 CAD per dose
Innovator 6
Innovator 6 is a widely used multivalent equine vaccine known for its established field track record and comprehensive antigen profile, which can reduce the total number of separate products needed in a vaccination program. While often priced above the most economical combos, its broad coverage and strong clinical data make it an attractive option for stables seeking a single, proven product rather than layering multiple vaccines from different manufacturers.
Six-disease cover — mega-guard
Single-dose practicality — ride-ready
Six-disease cover — mega-guard
Single-dose practicality — ride-ready
Review Summary
"Innovator 6 is viewed as a high-efficacy, comprehensive vaccine with good long-term performance; some users report slightly higher rates of mild adverse reactions but overall satisfaction is high."
Consistent immunity — pro-farmer favorite
Broad multivalent vaccine designed to protect against multiple encephalomyelitis agents and tetanus in one product.
Consistent immunity — pro-farmer favorite
Broad multivalent vaccine designed to protect against multiple encephalomyelitis agents and tetanus in one product.
Enhanced Physical Well-Being
Time-Saving Convenience
Recreational Enjoyment
Innovator 6 is a widely used multivalent equine vaccine known for its established field track record and comprehensive antigen profile, which can reduce the total number of separate products needed in a vaccination program. While often priced above the most economical combos, its broad coverage and strong clinical data make it an attractive option for stables seeking a single, proven product rather than layering multiple vaccines from different manufacturers.
Six-disease cover — mega-guard
Single-dose practicality — ride-ready
Consistent immunity — pro-farmer favorite
Broad multivalent vaccine designed to protect against multiple encephalomyelitis agents and tetanus in one product.
Often chosen for herd protocols to reduce the number of separate injections and veterinary visits.
Six-disease cover — mega-guard
Single-dose practicality — ride-ready
Consistent immunity — pro-farmer favorite
Broad multivalent vaccine designed to protect against multiple encephalomyelitis agents and tetanus in one product.
Often chosen for herd protocols to reduce the number of separate injections and veterinary visits.
$40-90 CAD per dose
Encevac TC-4
Encevac TC-4 targets encephalomyelitis specifically and is presented as a technically focused, potentially lower-cost choice for regions where viral encephalitis risk is the primary concern. Compared to full-spectrum multivalents on this list, Encevac TC-4 offers a narrower antigen set that can be financially advantageous for targeted use, though it may require pairing with other products for comprehensive routine equine care.
Focused encephalitis cover — neuro-ninja
Area-targeted use — marsh-smart
Focused encephalitis cover — neuro-ninja
Area-targeted use — marsh-smart
Review Summary
"Encevac TC-4 is considered effective by many who use it, but reviews are more mixed due to limited availability, variable local reactions, and less widespread user experience compared with mainstream brands."
Reliable dosing profile — stable-tested
Focused, higher-potency formulation aimed specifically at preventing equine encephalomyelitis strains and tetanus.
Reliable dosing profile — stable-tested
Focused, higher-potency formulation aimed specifically at preventing equine encephalomyelitis strains and tetanus.
Enhanced Physical Well-Being
Time-Saving Convenience
Recreational Enjoyment
Encevac TC-4 targets encephalomyelitis specifically and is presented as a technically focused, potentially lower-cost choice for regions where viral encephalitis risk is the primary concern. Compared to full-spectrum multivalents on this list, Encevac TC-4 offers a narrower antigen set that can be financially advantageous for targeted use, though it may require pairing with other products for comprehensive routine equine care.
Focused encephalitis cover — neuro-ninja
Area-targeted use — marsh-smart
Reliable dosing profile — stable-tested
Focused, higher-potency formulation aimed specifically at preventing equine encephalomyelitis strains and tetanus.
Frequently selected for horses at higher risk or in outbreak-prone areas to achieve stronger immune responses.
Focused encephalitis cover — neuro-ninja
Area-targeted use — marsh-smart
Reliable dosing profile — stable-tested
Focused, higher-potency formulation aimed specifically at preventing equine encephalomyelitis strains and tetanus.
Frequently selected for horses at higher risk or in outbreak-prone areas to achieve stronger immune responses.
$60-120 CAD per dose
West Nile-Innovator + EWT
West Nile-Innovator + EWT combines West Nile protection with EWT coverage in a single formulation, prioritizing convenience and reduced handling stress for horses through fewer injections. It competes directly with other combination products like Vetera by offering similar logistical benefits, while often leveraging the Innovator brand's reputation and distribution network to justify a mid-to-premium price point for practices that value supply reliability and consolidated vaccination protocols.
WNV + EWT combo — duo-defender
Vet-sparing schedule — fewer pricks
WNV + EWT combo — duo-defender
Vet-sparing schedule — fewer pricks
Review Summary
"The West Nile Innovator combined with EWT is seen as a convenient, effective approach that provides solid protection; users note routine post-vaccination soreness but report good immunity over repeated use."
Keeps show horses fit — ring-ready
Combines West Nile virus protection with EWT (Eastern/Western encephalomyelitis and tetanus) in a single dose.
Keeps show horses fit — ring-ready
Combines West Nile virus protection with EWT (Eastern/Western encephalomyelitis and tetanus) in a single dose.
Enhanced Physical Well-Being
Time-Saving Convenience
Recreational Enjoyment
West Nile-Innovator + EWT combines West Nile protection with EWT coverage in a single formulation, prioritizing convenience and reduced handling stress for horses through fewer injections. It competes directly with other combination products like Vetera by offering similar logistical benefits, while often leveraging the Innovator brand's reputation and distribution network to justify a mid-to-premium price point for practices that value supply reliability and consolidated vaccination protocols.
WNV + EWT combo — duo-defender
Vet-sparing schedule — fewer pricks
Keeps show horses fit — ring-ready
Combines West Nile virus protection with EWT (Eastern/Western encephalomyelitis and tetanus) in a single dose.
Simplifies vaccination schedules by reducing the number of separate injections required for broad encephalomyelitis coverage.
WNV + EWT combo — duo-defender
Vet-sparing schedule — fewer pricks
Keeps show horses fit — ring-ready
Combines West Nile virus protection with EWT (Eastern/Western encephalomyelitis and tetanus) in a single dose.
Simplifies vaccination schedules by reducing the number of separate injections required for broad encephalomyelitis coverage.
$50-100 CAD per dose