Trusopt (Dorzolamide) 2% Ophthalmic Solution
Trusopt is the reference-brand dorzolamide 2% aqueous solution with a long clinical track record and predictable topical carbonic anhydrase inhibition that veterinarians rely on for dogs. Its sterile solution formulation is easy to instill and generally causes less transient visual disturbance than suspensions, making it a practical and cost-effective branded choice compared with combination products and some suspension-based alternatives.
Rapid IOP drop
Low irritation
Rapid IOP drop
Low irritation
Review Summary
"Most long‑term users report reliable intraocular pressure reduction in dogs, though many note a transient stinging/burning on application; overall effective but often pricier than generics."
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Increased Safety & Security
Time-Saving Convenience
Trusopt is the reference-brand dorzolamide 2% aqueous solution with a long clinical track record and predictable topical carbonic anhydrase inhibition that veterinarians rely on for dogs. Its sterile solution formulation is easy to instill and generally causes less transient visual disturbance than suspensions, making it a practical and cost-effective branded choice compared with combination products and some suspension-based alternatives.
Rapid IOP drop
Low irritation
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Brand formulation with consistent drop size and preservative profile; often used off-label in dogs for glaucoma.
Rapid IOP drop
Low irritation
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Brand formulation with consistent drop size and preservative profile; often used off-label in dogs for glaucoma.
$35-80 CAD
Azopt (Brinzolamide) 1% Ophthalmic Suspension
Azopt is the market-leading brinzolamide 1% suspension, valued in canine ophthalmology for a formulation that can be more comfortable and less stinging than acidic aqueous solutions. Compared with dorzolamide brands, Azopt often provides similar carbonic anhydrase inhibition with a distinct suspension profile — a technical advantage for tolerability in some dogs but sometimes at a higher branded price than generic monotherapies.
Creamy suspension
Clear vision aid
Creamy suspension
Clear vision aid
Review Summary
"Owners and veterinarians commonly praise brinzolamide for solid IOP control with less stinging than dorzolamide, though the suspension can blur vision briefly and requires shaking."
Smooth pour — tail-wag!
Brinzolamide 1% ophthalmic suspension reduces aqueous humor production via carbonic anhydrase inhibition.
Smooth pour — tail-wag!
Brinzolamide 1% ophthalmic suspension reduces aqueous humor production via carbonic anhydrase inhibition.
Increased Safety & Security
Time-Saving Convenience
Azopt is the market-leading brinzolamide 1% suspension, valued in canine ophthalmology for a formulation that can be more comfortable and less stinging than acidic aqueous solutions. Compared with dorzolamide brands, Azopt often provides similar carbonic anhydrase inhibition with a distinct suspension profile — a technical advantage for tolerability in some dogs but sometimes at a higher branded price than generic monotherapies.
Creamy suspension
Clear vision aid
Smooth pour — tail-wag!
Brinzolamide 1% ophthalmic suspension reduces aqueous humor production via carbonic anhydrase inhibition.
Suspension formulation may be better tolerated by some animals but requires shaking before use to ensure uniform dosing.
Creamy suspension
Clear vision aid
Smooth pour — tail-wag!
Brinzolamide 1% ophthalmic suspension reduces aqueous humor production via carbonic anhydrase inhibition.
Suspension formulation may be better tolerated by some animals but requires shaking before use to ensure uniform dosing.
$40-90 CAD
Cosopt (Dorzolamide-Timolol) Ophthalmic Solution
Cosopt pairs dorzolamide with timolol to deliver combined CAI and beta-blocker effects in a single bottle, offering stronger intraocular pressure reduction potential for dogs than CAI monotherapy. Although typically more expensive and requiring attention to systemic beta-blocker considerations in veterinary patients, Cosopt’s combination dosing reduces administration complexity and can improve adherence and overall cost-effectiveness where dual-mechanism control is indicated.
Dual-action control
Broad pressure cut
Dual-action control
Broad pressure cut
Review Summary
"Users value Cosopt's superior IOP lowering and the convenience of combination therapy, but some report systemic beta‑blocker side effects (e.g., slowed heart rate) and note higher cost."
Power duo — superhero!
Combination dorzolamide–timolol provides dual mechanism: carbonic anhydrase inhibition plus beta-blockade for stronger intraocular pressure reduction.
Power duo — superhero!
Combination dorzolamide–timolol provides dual mechanism: carbonic anhydrase inhibition plus beta-blockade for stronger intraocular pressure reduction.
Increased Safety & Security
Time-Saving Convenience
Cosopt pairs dorzolamide with timolol to deliver combined CAI and beta-blocker effects in a single bottle, offering stronger intraocular pressure reduction potential for dogs than CAI monotherapy. Although typically more expensive and requiring attention to systemic beta-blocker considerations in veterinary patients, Cosopt’s combination dosing reduces administration complexity and can improve adherence and overall cost-effectiveness where dual-mechanism control is indicated.
Dual-action control
Broad pressure cut
Power duo — superhero!
Combination dorzolamide–timolol provides dual mechanism: carbonic anhydrase inhibition plus beta-blockade for stronger intraocular pressure reduction.
Single-bottle fixed-dose regimen can simplify dosing when both agents are indicated for canine glaucoma management.
Dual-action control
Broad pressure cut
Power duo — superhero!
Combination dorzolamide–timolol provides dual mechanism: carbonic anhydrase inhibition plus beta-blockade for stronger intraocular pressure reduction.
Single-bottle fixed-dose regimen can simplify dosing when both agents are indicated for canine glaucoma management.
$60-120 CAD
Dorzolamide 2% Generic Ophthalmic Solution
Generic dorzolamide 2% solutions provide the same active CAI ingredient as Trusopt but at lower acquisition cost, making them a budget-friendly option for long-term topical management of glaucoma in dogs. Manufacturing differences in preservatives and bottle design can slightly affect comfort, dosing convenience, or shelf life, but generics generally match branded pharmacologic efficacy while delivering meaningful financial savings for clinics and owners.
Budget-friendly pick
Equivalent efficacy
Budget-friendly pick
Equivalent efficacy
Review Summary
"Generic dorzolamide is generally reported to match brand efficacy at a lower cost, with occasional complaints about packaging, shelf life, or slightly increased stinging depending on manufacturer."
No-frills hero — yay!
Generic dorzolamide 2% offers the same active carbonic anhydrase inhibitory effect at a lower cost.
No-frills hero — yay!
Generic dorzolamide 2% offers the same active carbonic anhydrase inhibitory effect at a lower cost.
Increased Safety & Security
Time-Saving Convenience
Generic dorzolamide 2% solutions provide the same active CAI ingredient as Trusopt but at lower acquisition cost, making them a budget-friendly option for long-term topical management of glaucoma in dogs. Manufacturing differences in preservatives and bottle design can slightly affect comfort, dosing convenience, or shelf life, but generics generally match branded pharmacologic efficacy while delivering meaningful financial savings for clinics and owners.
Budget-friendly pick
Equivalent efficacy
No-frills hero — yay!
Generic dorzolamide 2% offers the same active carbonic anhydrase inhibitory effect at a lower cost.
Widely available and suitable for long-term off-label management of elevated intraocular pressure in dogs.
Budget-friendly pick
Equivalent efficacy
No-frills hero — yay!
Generic dorzolamide 2% offers the same active carbonic anhydrase inhibitory effect at a lower cost.
Widely available and suitable for long-term off-label management of elevated intraocular pressure in dogs.
$20-50 CAD
Brinzolamide 1% Generic Ophthalmic Suspension
Generic brinzolamide 1% suspensions reproduce Azopt’s active profile at reduced cost, offering an economical suspension option for canine patients who tolerate particulate formulations. Variability in particle size and viscosity across suppliers can influence transient blur or dosing consistency, yet generics remain attractive for practices seeking lower-cost brinzolamide therapy while accepting slight formulation trade-offs compared with the Azopt benchmark.
Affordable suspension
Dog-friendly texture
Affordable suspension
Dog-friendly texture
Review Summary
"Generic brinzolamide is seen as an affordable alternative to the brand with similar pressure control, though users sometimes report more sediment, the need for vigorous shaking, or variable bottle quality."
Value drop — paw-approved!
Generic brinzolamide 1% suspension provides cost-effective carbonic anhydrase inhibition for canine glaucoma.
Value drop — paw-approved!
Generic brinzolamide 1% suspension provides cost-effective carbonic anhydrase inhibition for canine glaucoma.
Increased Safety & Security
Time-Saving Convenience
Generic brinzolamide 1% suspensions reproduce Azopt’s active profile at reduced cost, offering an economical suspension option for canine patients who tolerate particulate formulations. Variability in particle size and viscosity across suppliers can influence transient blur or dosing consistency, yet generics remain attractive for practices seeking lower-cost brinzolamide therapy while accepting slight formulation trade-offs compared with the Azopt benchmark.
Affordable suspension
Dog-friendly texture
Value drop — paw-approved!
Generic brinzolamide 1% suspension provides cost-effective carbonic anhydrase inhibition for canine glaucoma.
Requires shaking before administration to ensure even suspension and consistent dosing.
Affordable suspension
Dog-friendly texture
Value drop — paw-approved!
Generic brinzolamide 1% suspension provides cost-effective carbonic anhydrase inhibition for canine glaucoma.
Requires shaking before administration to ensure even suspension and consistent dosing.
$25-60 CAD